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Amgen Inc. announced Thursday a research collaboration with privately held Generate Biomedicines to discover and create protein therapeutics, which could lead to a potential payment to Generate by Amgen of $1.9 billion. Under terms of the agreement, which is initially for five clinical target programs, Amgen said it will provide $50 million in upfront funding and will pay up to $370 million in future milestones and royalties for each program. Amgen will have the option to nominate up to five additional programs at additional cost. "We are now at a scientific hinge point, where computational approaches can advance our knowledge of biology and further drive our ability to design the right molecule for some of the most challenging targets," said David M. Reese, executive vice president of research and development at Amgen. "We believe Generate Biomedicine''s integrated in silico design and wet lab capabilities combined with Amgen''s strength in protein engineering can accelerate our drug discovery efforts, generating novel protein sequences with optimal therapeutic properties." Amgen''s stock, which slipped 0.1% in premarket trading, has rallied 7.2% over the past three months through Wednesday while the Dow Jones Industrial Average has gained 5.8%.

Dow futures crept higher but Nasdaq futures moved lower Thursday, one day after a major Federal Reserve-driven sell-off.

Global stocks and Wall Street futures tumbled Thursday after investors saw minutes from a Federal Reserve meeting as a sign the U.S. central bank might hike interest rates faster to cool inflation. Benchmarks in London and Frankfurt opened down more than 1% while Tokyo lost nearly 3%. Notes from the Fed meeting last month showed policymakers believe the U.S. job market is nearly healthy enough that ultra-low rates are no longer needed. Traders took that as a sign the Fed might be more aggressive about rolling back stimulus that is boosting stock prices. The report bludgeoned the markets by upsetting expectations that earlier Fed plans were locked in, Vishnu Varathan of Mizuho Bank said in a report. In early trading, the FTSE 100 in London lost 1.1% to 7,435.95. Frankfurt''s DAX fell 1.4% to 16,046.83 and the CAC 40 in Paris sank 1.6% to 7,255.16. On Wall Street, the future for the benchmark S&P 500 index was off 0.3% and that for the Dow Jones Industrial Average was down 0.2%. On

Equity CEFs: Top Picks For 2022

At the close of trade, the Dow Jones Industrial Average index stumbled 392.54 points, or 1.07%, to 36,407.11. The S&P500 index retreated 92.96 points, or 1.94%, to 4,700.58. The tech-heavy Nasdaq Composite Index declined 522.54 points, or 3.34%, to 15,100.17.

"There are a few comeback stories in the dogs of the Dow, but for the most part I don''t expect these dogs to have their day in 2022," the "Mad Money" host said.

The Dow Jones Industrial Average saw its first decline of 2022 overnight as traders geared up for potentially tighter U.S. monetary policy.

The Dow Jones Industrial Average saw its first decline of 2022 overnight as traders geared up for potentially tighter U.S. monetary policy.

This Dow Jones ETF hits a new 52-week high. Are more gains in store for this ETF?

To find solid independent market analysis and investment ideas, I like to regularly consult those unsung market heroes — stock newsletter writers.

U.S. stocks remained level today fueled by a 0.3% decline in large cap stocks and a 0.6% decline in telecom stocks. The S&P 500 Index is currently up 0.6% year-to-date, and up 29.5% over the past 12 months. The Dow Jones Industrial Average is currently up 0.6% year-to-date, and up 21.6% over the past 12 months. Elsewhere, commodities climbed 1.1% with gold rising 0.8%, crude oil rising 1.2% and copper rising 1.1%. The yield on 10-year Treasuries is 1.52%, while the dollar strengthened by 0.1% against a basket of other currencies. Meanwhile, investment grade corporate bonds rose by 0.1%, and high yield bonds fell by 0.3%. Stocks The S&P 500 Index stayed level. The Dow Jones Industrial Average stayed level. The Nasdaq Composite Index declined 1.5%. The Nasdaq 100 Index declined 1.3%. The Volatility Index declined 0.1%. Large cap stocks, as represented by the S&P 100 Index, declined 0.3%. Mid cap stocks, as represented by the S&P MidCap 400 Index, rose 0.5%. Small cap stocks, as represented by the S&P SmallCap 600 Index, rose 0.8%. Sectors Stocks in the Consumer Discretionary sector rose the most with a stayed level. Stocks in the Telecom sector fell the most with a 0.6% decline. With a 294.8% gain, stocks in the Technology sector have advanced the most over the past 5 years With a 13.9% decline, stocks in the Energy sector have declined the most over the past 5 years Bonds The yield on 1-year Treasuries increased by 1 basis point to 0.39% today. The yield on 5-year Treasuries decreased by 3 basis points to 1.26% today. The yield on 10-year Treasuries decreased by 3 basis points to 1.52% today. The yield on 30-year Treasuries decreased by 6 basis points to 1.9% today. Credit Investment grade corporate bonds tracked by the Markit iBoxx USD Liquid Investment Grade Index rose by 0.1%. High yield bonds tracked by the Markit iBoxx USD Liquid High Yield Index fell by 0.3%. Emerging market bonds tracked by the J.P. Morgan Emerging Markets Core Index fell by 0.1%. Commodities The S&P GSCI Total Return Index, the leading measure of general commodity price movements, rose by 1.1% West Texas Intermediate crude oil rose by 1.2%. Brent crude oil rose by 1.4%. Gold rose by 0.8%. Copper rose by 1.1%. Silver rose by 0.7%. Currencies The Deutsche Bank Long US Dollar Index, which measures the greenback against a basket of other currencies, strengthened by 0.1% to $25.81 today. The Euro weakened by 0.1% to $1.13. The British pound strengthened by 0.3% to $1.35. The Japanese yen strengthened by 0.7% to 116.13 per dollar. Cryptocurrencies Bitcoin declined by 0.2% to $46200 today. Ethereum rose by 1.4% to $3820.04 today. Tether declined by 0.1% to $0.9995672868887927 today. XRP declined by 0.6% to $0.83 today. This story was produced by the Kwhen Automated News Generator. For more articles like this, please visit us at finance.kwhen.com. Write to [email protected]. © 2020 Kwhen Inc.

U.S. stocks rose by 0.3% today fueled by a 1.1% increase in large cap stocks and a 3.1% increase in energy stocks. The S&P 500 Index is currently flat year-to-date, and up 28.7% over the past 12 months. The Dow Jones Industrial Average is currently flat year-to-date, and up 20.8% over the past 12 months. Elsewhere, commodities climbed 0.4% with gold falling 1.6%, crude oil rising 1.4% and copper falling 0.9%. The yield on 10-year Treasuries is 1.55%, while the dollar strengthened by 0.6% against a basket of other currencies. Meanwhile, investment grade corporate bonds fell by 1.1%, and high yield bonds fell by 0.0%. Stocks The S&P 500 Index rose 0.3%. The Dow Jones Industrial Average rose 0.4%. The Nasdaq Composite Index rose 1.0%. The Nasdaq 100 Index rose 1.0%. The Volatility Index declined 3.4%. Large cap stocks, as represented by the S&P 100 Index, rose 1.1%. Mid cap stocks, as represented by the S&P MidCap 400 Index, rose 0.3%. Small cap stocks, as represented by the S&P SmallCap 600 Index, rose 1.1%. Sectors Stocks in the Energy sector rose the most with a 3.1% gain. Stocks in the Health Care sector fell the most with a 1.4% decline. With a 295.8% gain, stocks in the Technology sector have advanced the most over the past 5 years With a 15.3% decline, stocks in the Energy sector have declined the most over the past 5 years Bonds The yield on 1-year Treasuries remained unchanged at 0.38% today. The yield on 5-year Treasuries remained unchanged at 1.29% today. The yield on 10-year Treasuries remained unchanged at 1.55% today. The yield on 30-year Treasuries remained unchanged at 1.96% today. Credit Investment grade corporate bonds tracked by the Markit iBoxx USD Liquid Investment Grade Index fell by 1.1%. High yield bonds tracked by the Markit iBoxx USD Liquid High Yield Index fell by 0.0%. Emerging market bonds tracked by the J.P. Morgan Emerging Markets Core Index fell by 1.0%. Commodities The S&P GSCI Total Return Index, the leading measure of general commodity price movements, rose by 0.4% West Texas Intermediate crude oil rose by 1.4%. Brent crude oil rose by 1.2%. Gold declined by 1.6%. Copper declined by 0.9%. Silver declined by 1.5%. Currencies The Deutsche Bank Long US Dollar Index, which measures the greenback against a basket of other currencies, strengthened by 0.6% to $25.79 today. The Euro weakened by 0.7% to $1.13. The British pound weakened by 0.3% to $1.35. The Japanese yen strengthened by 0.2% to 115.35 per dollar. Cryptocurrencies Bitcoin declined by 0.1% to $46300.01 today. Ethereum rose by 2.3% to $3768.62 today. Tether rose by 0.0% to $1.0001898848204909 today. XRP rose by 0.7% to $0.84 today. This story was produced by the Kwhen Automated News Generator. For more articles like this, please visit us at finance.kwhen.com. Write to [email protected]. © 2020 Kwhen Inc.

The accelerated levels of the coronavirus vaccine rollout and strongly rebounding U.S. economy from the pandemic-led slowdown should support the market sentiments in 2022.

Comparing the Dow Dogs performance to the DJIA Index, the largest detractor to the strategy's performance was the 412 basis point underperformance in the Health Care sector. Energy and Information Tec

Pre-market indexes are picking up 2021's solid growth numbers to start 2022 trading this morning.