NASDAQ:PYXS

Pyxis Oncology Stock Forecast

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$2.77
+0.540 (+24.22%)
At Close: Jun 26, 2026
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  • +151.8% price growth over the last year
  • High gross margin of 99.8%
  • +140.9% YTD performance
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High volatility in Pyxis Oncology, Inc. stock price on Friday which ended trading at $2.77
(Updated on Jun 26, 2026)

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Buy or Hold candidate since Jun 18, 2026 Gain 36.45%

The Pyxis Oncology, Inc. stock price gained 24.22% on the last trading day (Friday, 26th Jun 2026), rising from $2.23 to $2.77. It has now gained 3 days in a row. It will be exciting to see whether it manages to continue gaining or take a minor break for the next few days. During the last trading day the stock fluctuated 36.25% from a day low at $2.20 to a day high of $3.00. The price has risen in 8 of the last 10 days and is up by 65.87% over the past 2 weeks. Volume fell on the last day by -666 thousand shares and in total, 0 shares were bought and sold for approximately $0 . You should take into consideration that falling volume on higher prices causes divergence and may be an early warning about possible changes over the next couple of days.

The stock lies in the upper part of a very wide and strong rising trend in the short term, and this may normally pose a very good selling opportunity for the short-term trader as reaction back towards the lower part of the trend can be expected. A break-up at the top trend line at $3.01 will firstly indicate a stronger rate of rising. Given the current short-term trend, the stock is expected to rise 19.95% during the next 3 months and, with a 90% probability hold a price between $2.00 and $3.61 at the end of this 3-month period.

PYXS Signals & Forecast

The Pyxis Oncology, Inc. stock holds buy signals from both short and long-term Moving Averages giving a positive forecast for the stock. Also, there is a general buy signal from the relation between the two signals where the short-term average is above the long-term average. On corrections down, there will be some support from the lines at $2.19 and $2.01. A breakdown below any of these levels will issue sell signals. A buy signal was issued from a pivot bottom point on Wednesday, June 10, 2026, and so far it has risen 65.87%. Further rise is indicated until a new top pivot has been found. Furthermore, there is a buy signal from the 3 month Moving Average Convergence Divergence (MACD). Some negative signals were issued as well, and these may have some influence on the near short-term development. Volume fell during the last trading day while the price increased. This causes a divergence and may be considered as an early warning, but it may not be. The very low volume increases the risk and reduces the other technical signals issued.

Support, Risk & Stop-loss for Pyxis Oncology, Inc. stock

Pyxis Oncology, Inc. finds support from accumulated volume at $2.74 and this level may hold a buying opportunity as an upwards reaction can be expected when the support is being tested.

In general the stock tends to have very controlled movements and therefore the general risk is considered very low. However, be aware of low or falling volume and make sure to keep an eye on the stock During the last day, the stock moved $0.798 between high and low, or 36.25%. For the last week the stock has had daily average volatility of 14.16%

The Pyxis Oncology, Inc. stock is overbought on RSI14 and lies in the upper part of the trend. Normally this may pose a good selling opportunity for the short-term trader, but some stocks may go long and hard while being overbought. Regardless, the high RSI together with the trend position increases the risk and higher daily movements (volatility) should be expected. A correction down in the nearby future seems very likely and it is of great importance that the stock manages to break the trend before that occurs.

Our recommended stop-loss: $2.69 (-2.76%) (This stock has very low daily movements and this gives very low risk. The RSI14 is 87 and this increases the risk substantially. There is a buy signal from a pivot bottom found 11 days ago.)

Trading Expectations (PYXS) For The Upcoming Trading Day Of Monday 29th

For the upcoming trading day on Monday, 29th we expect Pyxis Oncology, Inc. to open at $2.66, and during the day (based on 14 day Average True Range), to move between $2.66 and $2.88, which gives a possible trading interval of +/-$0.225 (+/-8.48%) up or down from last closing price. If Pyxis Oncology, Inc. takes out the full calculated possible swing range there will be an estimated 8.48% move between the lowest and the highest trading price during the day.

With no resistance above and support from accumulated volume @ $2.74, some $0.0300 (1.08%) from the current price of $2.77, our system finds the risk reward attractive.

Is Pyxis Oncology, Inc. stock A Buy?

Pyxis Oncology, Inc. holds several positive signals, but we still don't find these to be enough for a buy candidate. At the current level, it should be considered as a hold candidate (hold or accumulate) in this position whilst awaiting further development. Due to some small weaknesses in the technical picture we have downgraded our analysis conclusion for this stock since the last evaluation from a Strong Buy to a Hold candidate.

Current score: 0.000 Hold/Accumulate Downgraded

Zero in score indicates that our system is expecting high volatility and risk for the following trading day. Given the latest developments, we cannot determine the next direction as it may go both ways.

Predicted Fair Opening Price

Predicted fair opening price on June 29, 2026 - $2.66 ( 4.07%).

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PYXS Performance

Trading levels for PYXS

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Fibonacci Support & Resistance Levels

Level Price
R3 3.46 24.74%
R2 3.15 13.74%
R1 2.96 6.94%
Price 2.77
S1 2.35 -15.07%
S2 2.16 -21.87%
S3 1.86 -32.88%

Accumulated Volume Support & Resistance Levels

Level Price
R3 0 -
R2 0 -
R1 0 -
Price 2.77
S1 2.74 -1.08%
S2 2.30 -16.97%
S3 2.21 -20.22%

FAQ

What is the symbol for Pyxis Oncology, Inc. Stock and on which exchange is it traded?
The symbol for Pyxis Oncology, Inc. is PYXS and it is traded on the NASDAQ (NASDAQ Stock Exchange).

Should I buy or sell Pyxis Oncology, Inc. Stock?
Pyxis Oncology, Inc. holds several positive signals, but we still don't find these to be enough for a buy candidate. At the current level, it should be considered as a hold candidate (hold or accumulate) in this position whilst awaiting further development. Due to some small weaknesses in the technical picture we have downgraded our analysis conclusion for this stock since the last evaluation from a Strong Buy to a Hold candidate.

How to buy Pyxis Oncology, Inc. Stock?
Pyxis Oncology, Inc. Stock can be purchased through just about any brokerage firm, including online brokerage services.
Click here for our free guide on how to buy Pyxis Oncology, Inc. Stock.

What's the current price of Pyxis Oncology, Inc. Stock?
As of the end of day on the Jun 26, 2026, the price of an Pyxis Oncology, Inc. (PYXS) share was $2.77.

What is the 52-week high and low for Pyxis Oncology, Inc. Stock?
The 52-week high for Pyxis Oncology, Inc. Stock is $5.55 and the 52-week low is $0.97.

What is the market capitalization of Pyxis Oncology, Inc. Stock?
As of the Jun 26, 2026, the market capitalization of Pyxis Oncology, Inc. is 175.495M.

When is the next earnings date for Pyxis Oncology, Inc.?
The upcoming earnings date for Pyxis Oncology, Inc. is Aug 13, 2026.
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ABOUT PYXIS ONCOLOGY, INC.
Pyxis Oncology
Pyxis Oncology, Inc., a preclinical stage biopharmaceutical company, engages in the development of therapies to treat cancers. Its immune-oncology product candidates include PYX-106, an investigational fully human immunoglobulin G1 isotype siglec-15 targeting antibody for the treatment of thyroid cancer, head and neck squamous cell carcinoma, non-small cell lung cancer (NSCLC), and other solid tumors; and PYX-102, an investigational immune-therap...
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