- High gross margin of 86.3%
- Strong operating margin of 39.0%
- Healthy interest coverage ratio of 463.7x
Vertex Pharmaceuticals Incorporated stock price ended at $428.34 on Wednesday, after gaining 0.765%
(Updated on Jun 03, 2026)
The Vertex Pharmaceuticals Incorporated stock price gained 0.765% on the last trading day (Wednesday, 3rd Jun 2026), rising from $425.09 to $428.34. During the last trading day the stock fluctuated 2.14% from a day low at $420.01 to a day high of $429.01. The price has risen in 6 of the last 10 days but is still down by -1.37% for this period. Volume has increased on the last day along with the price, which is a positive technical sign, and, in total, 178 thousand more shares were traded than the day before. In total, 1 million shares were bought and sold for approximately $567.26 million.
The stock lies in the middle of a wide and falling trend in the short term and further fall within the trend is signaled. Given the current short-term trend, the stock is expected to fall -7.34% during the next 3 months and, with a 90% probability hold a price between $379.18 and $430.59 at the end of this 3-month period.
VRTX Signals & Forecast
A buy signal was issued from a pivot bottom point on Wednesday, April 29, 2026, and so far it has risen 1.20%. Further rise is indicated until a new top pivot has been found. Volume is rising along with the price. This is considered to be a good technical signal. Some negative signals were issued as well, and these may have some influence on the near short-term development. The Vertex Pharmaceuticals Incorporated stock holds sell signals from both short and long-term Moving Averages giving a more negative forecast for the stock. On corrections up, there will be some resistance from the lines at $437.21 and $434.82. A break-up above any of these levels will issue buy signals. Furthermore, there is currently a sell signal from the 3 month Moving Average Convergence Divergence (MACD).
Support, Risk & Stop-loss for Vertex Pharmaceuticals Incorporated stock
Vertex Pharmaceuticals Incorporated finds support from accumulated volume at $427.65 and this level may hold a buying opportunity as an upwards reaction can be expected when the support is being tested.
This stock is usually traded at a good volume, and with minor daily changes, the risk is considered to be low. During the last day, the stock moved $9.00 (2.14%) between high and low. For the last week, the stock has had daily average volatility of 2.38%.
Our recommended stop-loss: We hold a negative evaluation for this stock. No stop-loss is set.
Trading Expectations (VRTX) For The Upcoming Trading Day Of Thursday 4th
For the upcoming trading day on Thursday, 4th we expect Vertex Pharmaceuticals Incorporated to open at $425.79, and during the day (based on 14 day Average True Range), to move between $422.95 and $433.73, which gives a possible trading interval of +/-$10.78 (+/-2.55%) up or down from last closing price. If Vertex Pharmaceuticals Incorporated takes out the full calculated possible swing range there will be an estimated 2.55% move between the lowest and the highest trading price during the day.
Since the stock is closer to the support from accumulated volume at $427.65 (0.16%) than the resistance at $433.07 (1.10%), our systems sees the trading risk/reward intra-day as attractive and believe profit can be made before the stock reaches first resistance..
Is Vertex Pharmaceuticals Incorporated stock A Buy?
Vertex Pharmaceuticals Incorporated holds several negative signals and is within a wide and falling trend, so we believe it will still perform weakly in the next couple of days or weeks. We therefore hold a negative evaluation of this stock.
Current score:
-2.889
Sell Candidate
Unchanged
Predicted Fair Opening Price
Predicted fair opening price on June 4, 2026 - $425.79 ( 0.596%).
Want to trade but not sure how?
Our step-by-step guide can help.
Skip the guide? Open account with our trusted broker* 
*Your capital is at risk
VRTX Performance
Trading levels for VRTX
Fibonacci Support & Resistance Levels
| Level | Price | |
|---|---|---|
| R3 | 434.79 | 1.51% |
| R2 | 431.35 | 0.702% |
| R1 | 429.22 | 0.207% |
| Price | 428.34 | |
| S1 | 422.35 | -1.40% |
| S2 | 420.22 | -1.89% |
| S3 | 416.79 | -2.70% |
Accumulated Volume Support & Resistance Levels
| Level | Price | |
|---|---|---|
| R3 | 499.17 | 16.54% |
| R2 | 492.38 | 14.95% |
| R1 | 433.07 | 1.10% |
| Price | 428.34 | |
| S1 | 427.65 | -0.161% |
| S2 | 425.09 | -0.759% |
| S3 | 424.36 | -0.93% |
FAQ
Click here for our free guide on how to buy Vertex Pharmaceuticals Incorporated Stock.
Buy VRTX