Vertex Pharmaceuticals Stock Forecast

Buy candidate since Nov 10, 2025 Gain 3.04%

The Vertex Pharmaceuticals Incorporated stock price fell by -0.716% on the last day (Monday, 17th Nov 2025) from $437.15 to $434.02. During the last trading day the stock fluctuated 1.78% from a day low at $432.28 to a day high of $439.99. The price has been going up and down for this period, and there has been a 1.88% gain for the last 2 weeks. Volume fell on the last day along with the stock, which is actually a good sign as volume should follow the stock. On the last day, the trading volume fell by -26 thousand shares and in total, 1 million shares were bought and sold for approximately $537.75 million.

The stock lies in the upper part of a strong rising trend in the short term, and this may normally pose a very good selling opportunity for the short-term trader as reaction back towards the lower part of the trend can be expected. A break-up at the top trend line at $437.86 will firstly indicate a stronger rate of rising. Given the current short-term trend, the stock is expected to rise 11.61% during the next 3 months and, with a 90% probability hold a price between $450.53 and $488.69 at the end of this 3-month period.

VRTX Signals & Forecast

The Vertex Pharmaceuticals Incorporated stock holds buy signals from both short and long-term Moving Averages giving a positive forecast for the stock. Also, there is a general buy signal from the relation between the two signals where the short-term average is above the long-term average. On corrections down, there will be some support from the lines at $428.54 and $417.70. A breakdown below any of these levels will issue sell signals. Furthermore, there is a buy signal from the 3 month Moving Average Convergence Divergence (MACD). Some negative signals were issued as well, and these may have some influence on the near short-term development. A sell signal was issued from a pivot top point on Friday, November 14, 2025, and so far it has fallen -0.716%. Further fall is indicated until a new bottom pivot has been found. Volume fell together with the price during the last trading day and this reduces the overall risk as volume should follow the price movements.

Support, Risk & Stop-loss for Vertex Pharmaceuticals Incorporated stock

Vertex Pharmaceuticals Incorporated finds support from accumulated volume at $421.67 and this level may hold a buying opportunity as an upwards reaction can be expected when the support is being tested.

In general the stock tends to have very controlled movements and with good liquidity the risk is considered very low in this stock. During the last day, the stock moved $7.71 between high and low, or 1.78%. For the last week the stock has had daily average volatility of 2.32%.

Our recommended stop-loss: $416.26 (-4.09%) (This stock has very low daily movements and this gives very low risk. There is a sell signal from a pivot top found 1 day ago.)

Trading Expectations (VRTX) For The Upcoming Trading Day Of Tuesday 18th

For the upcoming trading day on Tuesday, 18th we expect Vertex Pharmaceuticals Incorporated to open at $435.43, and during the day (based on 14 day Average True Range), to move between $428.81 and $439.23, which gives a possible trading interval of +/-$10.42 (+/-2.43%) up or down from last closing price. If Vertex Pharmaceuticals Incorporated takes out the full calculated possible swing range there will be an estimated 2.43% move between the lowest and the highest trading price during the day.

Since the stock is closer to the resistance from accumulated volume at $434.19 (0.04%) than the support at $421.67 (2.85%), our systems don't find the trading risk/reward intra-day attractive and any bets should be held until the stock is closer to the support level.

Is Vertex Pharmaceuticals Incorporated stock A Buy?

Several short-term signals, along with a general good trend, are positive and we conclude that the current level may hold a buying opportunity as there is a fair chance for Vertex Pharmaceuticals Incorporated stock to perform well in the short-term. Due to some small weaknesses in the technical picture we have downgraded our analysis conclusion for this stock since the last evaluation from a Strong Buy to a Buy candidate.

Current score: 2.913 Buy Candidate Downgraded

Predicted Fair Opening Price

Predicted fair opening price on November 18, 2025 - $435.43 ( 0.325%).

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