NYSE:ANVS

Annovis Bio Stock Insider Trading

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$1.86
+0.0400 (+2.20%)
At Close: Jun 02, 2026

Annovis Bio Stock Insider Power

Based on the 100 latest insides trades, we have calculated the insider power to be positive at 100.00. In total, the insiders bought 4.13M and sold 66K ANVS shares in the last 100 trades. The insider score can be negative despite buy/sell ratio being positive. The score focuses on the quality of the trades.

Insider Power

(Last 100 transactions)
100.00
Buy 4.13M shares
Sell 66K shares
92% Buy Activity
Negligible or No Correlation

No Significant Signals

No statistically significant buy or sell signals detected in recent insider data.

Historical Insider Trades

Date Type Person Role Amount
Nov 20, 2023
Buy
Common Stock
A-Award
Mccarthy Reid
Director
Director 824
Value: $5K
Nov 20, 2023
Buy
Common Stock
A-Award
Hoffman Michael B
Director 164 745
Value: $1.00M
Nov 20, 2023
Buy
Common Stock
A-Award
White Mark K.
Director
Director 2 000
Value: $12.1K
Nov 20, 2023
Buy
Common Stock
A-Award
Maccecchini Maria-luisa
President And CEO
CEO / President 41 186
Value: $250.0K
Nov 20, 2023
Buy
Common Stock
A-Award
Hagopian Henry Iii
Chief Financial Officer
C-Suite Officer 824
Value: $5K
Nov 20, 2023
Buy
Common Stock
A-Award
Bruck Claudine
Director
Director 1 000
Value: $6K
Nov 20, 2023
Buy
Common Stock
A-Award
Bruck Claudine
Director
Director 1 000
Value: $6K
Nov 20, 2023
Buy
Common Stock
A-Award
Hagopian Henry Iii
Chief Financial Officer
C-Suite Officer 824
Value: $5K
Nov 20, 2023
Buy
Common Stock
A-Award
White Mark K.
Director
Director 2 000
Value: $12.1K
Nov 20, 2023
Buy
Common Stock
A-Award
Hoffman Michael B
Director 164 745
Value: $1.00M
Nov 17, 2023
Buy
Stock Option (right to buy)
A-Award
Maccecchini Maria-luisa
President And CEO
CEO / President 252 000
Value: $1.53M
Nov 17, 2023
Buy
Stock Option (right to buy)
A-Award
Maccecchini Maria-luisa
President And CEO
CEO / President 108 800
Value: $660.4K
Nov 17, 2023
Buy
Stock Option (right to buy)
A-Award
Hoffman Michael B
Director 29 600
Value: $179.7K
Nov 17, 2023
Buy
Stock Option (right to buy)
A-Award
Bruck Claudine
Director
Director 26 200
Value: $159.0K
Nov 17, 2023
Buy
Stock Option (right to buy)
A-Award
White Mark K.
Director
Director 26 200
Value: $159.0K
Nov 17, 2023
Buy
Stock Option (right to buy)
A-Award
Mccarthy Reid
Director
Director 29 600
Value: $179.7K
Nov 17, 2023
Buy
Stock Option (right to buy)
A-Award
Bruck Claudine
Director
Director 26 200
Value: $159.0K
Nov 17, 2023
Buy
Stock Option (right to buy)
A-Award
Hoffman Michael B
Director 29 600
Value: $179.7K
Nov 17, 2023
Buy
Stock Option (right to buy)
A-Award
Maccecchini Maria-luisa
President And CEO
CEO / President 108 800
Value: $660.4K
Nov 17, 2023
Buy
Stock Option (right to buy)
A-Award
Maccecchini Maria-luisa
President And CEO
CEO / President 252 000
Value: $1.53M
Nov 17, 2023
Buy
Stock Option (right to buy)
A-Award
Mccarthy Reid
Director
Director 29 600
Value: $179.7K
Nov 17, 2023
Buy
Stock Option (right to buy)
A-Award
White Mark K.
Director
Director 26 200
Value: $159.0K
Apr 24, 2023
Sell
Common Stock
G-Gift
Maccecchini Maria-luisa
President And CEO
CEO / President 3 000
Value: $0
Apr 24, 2023
Sell
Common Stock
G-Gift
Maccecchini Maria-luisa
President And CEO
CEO / President 3 000
Value: $0
Apr 07, 2023
Buy
Common Stock
A-Award
Maccecchini Maria-luisa
President And CEO
CEO / President 20 000
Value: $252.2K

About Insider Power

Insider Power is a proprietary algorithm developed by StockInvest.us to evaluate the significance of insider transactions. The calculation considers the size, type, and timing of transactions, as well as the insider’s role within the company.

It is important to note that, in general, there is little to no correlation between insider transactions and short-term stock price movements. In one of our studies, only 0.22%* of stocks with insider activity showed a measurable correlation — and even then, it was unclear whether the effect was caused by insider actions or simply by the stock’s broader trend.

While our algorithms are designed to highlight potentially meaningful signals, these cannot be regarded as statistically significant on their own. Insider trading activity should therefore be seen as informative rather than as direct trading guidance. The Insider Power metric was created to present this information in a clearer and more accessible way, helping investors better understand the possible context of insider activity.

* October 6th, 2025 - Tested on 5562 stocks

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ABOUT ANNOVIS BIO, INC.
Annovis Bio
Annovis Bio, Inc., a clinical stage drug platform company, develops drugs to treat neurodegeneration. The company's lead compound is Buntanetap, an orally administered drug, which has completed Phase 2a clinical trials for the treatment of Alzheimer's disease (AD) and Parkinson's disease, as well as is in clinical trials for Alzheimer's disease in Down Syndrome and other chronic neurodegenerative disorders. It is also developing ANVS405 for prote...
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