NASDAQ:AXSM

Axsome Therapeutics Stock Insider Trading

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$233.49
+11.33 (+5.10%)
At Close: Jun 03, 2026

Axsome Therapeutics Stock Insider Power

Based on the 100 latest insides trades, we have calculated the insider power to be negative at -79.16. In total, the insiders bought 1.56M and sold 667.52K AXSM shares in the last 100 trades. The insider score can be negative despite buy/sell ratio being positive. The score focuses on the quality of the trades.

Insider Power

(Last 100 transactions)
-79.16
Buy 1.56M shares
Sell 667.52K shares
71% Buy Activity
Moderate Negative Correlation
Buy Signal Low Confidence
Apr 21, 2026

Analysis Breakdown:

  • Signal is highly questionable due to a strongly contradictory negative Insider Power Score of -79.16.
  • Confidence increased due to high data reliability score of 100.

Historical Insider Trades

Date Type Person Role Amount
Dec 31, 2025
Buy
Common Stock
M-Exempt
Saad Mark E
Director
Director 31 346
Value: $155.2K
Dec 31, 2025
Buy
Common Stock
M-Exempt
Saad Mark E
Director
Director 6 231
Value: $50.0K
Dec 31, 2025
Sell
Common Stock
S-Sale
Saad Mark E
Director
Director 31 346
Value: $5.18M
Dec 31, 2025
Buy
Stock Option (Right to Buy)
M-Exempt
Saad Mark E
Director
Director 6 231
Value: $50.0K
Dec 31, 2025
Buy
Stock Option (Right to Buy)
M-Exempt
Saad Mark E
Director
Director 31 346
Value: $155.2K
Dec 04, 2025
Sell
Common Stock
S-Sale
Tabuteau Herriot
Chief Executive Officer
CEO / President 10 558
Value: $1.56M
Dec 04, 2025
Buy
Common Stock
M-Exempt
Tabuteau Herriot
Chief Executive Officer
CEO / President 10 558
Value: $84.7K
Dec 04, 2025
Buy
Stock Option (Right to Buy)
M-Exempt
Tabuteau Herriot
Chief Executive Officer
CEO / President 10 558
Value: $1.56M
Dec 03, 2025
Sell
Common Stock
S-Sale
Tabuteau Herriot
Chief Executive Officer
CEO / President 20 163
Value: $2.96M
Dec 03, 2025
Buy
Common Stock
M-Exempt
Tabuteau Herriot
Chief Executive Officer
CEO / President 20 163
Value: $161.7K
Dec 03, 2025
Buy
Stock Option (Right to Buy)
M-Exempt
Tabuteau Herriot
Chief Executive Officer
CEO / President 20 163
Value: $2.96M
Dec 02, 2025
Buy
Common Stock
M-Exempt
Tabuteau Herriot
Chief Executive Officer
CEO / President 49 252
Value: $395.0K
Dec 02, 2025
Buy
Stock Option (Right to Buy)
M-Exempt
Tabuteau Herriot
Chief Executive Officer
CEO / President 49 252
Value: $7.12M
Dec 02, 2025
Sell
Common Stock
S-Sale
Tabuteau Herriot
Chief Executive Officer
CEO / President 49 252
Value: $7.12M
Nov 05, 2025
Buy
Stock Option (Right to Buy)
M-Exempt
Tabuteau Herriot
Chief Executive Officer
CEO / President 21 775
Value: $2.93M
Nov 05, 2025
Buy
Common Stock
M-Exempt
Tabuteau Herriot
Chief Executive Officer
CEO / President 21 775
Value: $174.6K
Nov 05, 2025
Sell
Common Stock
S-Sale
Tabuteau Herriot
Chief Executive Officer
CEO / President 21 775
Value: $2.93M
Nov 04, 2025
Buy
Stock Option (Right to Buy)
M-Exempt
Tabuteau Herriot
Chief Executive Officer
CEO / President 50 459
Value: $6.75M
Nov 04, 2025
Buy
Common Stock
M-Exempt
Tabuteau Herriot
Chief Executive Officer
CEO / President 50 459
Value: $404.7K
Nov 04, 2025
Sell
Common Stock
S-Sale
Tabuteau Herriot
Chief Executive Officer
CEO / President 50 459
Value: $6.75M
Nov 03, 2025
Buy
Common Stock
M-Exempt
Tabuteau Herriot
Chief Executive Officer
CEO / President 91 705
Value: $735.5K
Nov 03, 2025
Buy
Stock Option (Right to Buy)
M-Exempt
Tabuteau Herriot
Chief Executive Officer
CEO / President 91 705
Value: $12.1M
Nov 03, 2025
Sell
Common Stock
S-Sale
Tabuteau Herriot
Chief Executive Officer
CEO / President 91 705
Value: $12.1M
Oct 08, 2025
Buy
Stock Option (Right to Buy)
M-Exempt
Tabuteau Herriot
Chief Executive Officer
CEO / President 12 774
Value: $1.52M
Oct 08, 2025
Buy
Common Stock
M-Exempt
Tabuteau Herriot
Chief Executive Officer
CEO / President 12 774
Value: $102.4K

About Insider Power

Insider Power is a proprietary algorithm developed by StockInvest.us to evaluate the significance of insider transactions. The calculation considers the size, type, and timing of transactions, as well as the insider’s role within the company.

It is important to note that, in general, there is little to no correlation between insider transactions and short-term stock price movements. In one of our studies, only 0.22%* of stocks with insider activity showed a measurable correlation — and even then, it was unclear whether the effect was caused by insider actions or simply by the stock’s broader trend.

While our algorithms are designed to highlight potentially meaningful signals, these cannot be regarded as statistically significant on their own. Insider trading activity should therefore be seen as informative rather than as direct trading guidance. The Insider Power metric was created to present this information in a clearer and more accessible way, helping investors better understand the possible context of insider activity.

* October 6th, 2025 - Tested on 5562 stocks

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ABOUT AXSOME THERAPEUTICS
Axsome Therapeutics
Axsome Therapeutics, Inc., a biopharmaceutical company, engages in the development of novel therapies for central nervous system (CNS) disorders in the United States. The company's product pipeline includes AXS-05, a therapeutic for the treatment of major depressive disorder and resistant depression disorders; and that is in the Phase III clinical trial to treat Alzheimer's disease agitation, as well as that has completed phase II clinical trial ...
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