NASDAQ:UPB

Upstream Bio Stock Insider Trading

etoro logo Buy UPB
*Your capital is at risk
$6.74
-0.0500 (-0.736%)
At Close: Aug 05, 2026

Upstream Bio Stock Insider Power

Based on the 38 latest insides trades, we have calculated the insider power to be positive at 91.56. In total, the insiders bought 1.03M and sold 10.03K UPB shares in the last 38 trades. The insider score can be negative despite buy/sell ratio being positive. The score focuses on the quality of the trades.

Insider Power

(Last 38 transactions)
91.56
Buy 1.03M shares
Sell 10.03K shares
74% Buy Activity
Negligible or No Correlation
Sell Signal Low Confidence
Jun 16, 2026

Analysis Breakdown:

  • Signal is highly questionable due to a strongly contradictory positive Insider Power Score of 91.56.
  • Confidence increased due to high data reliability score of 90.

Historical Insider Trades

Date Type Person Role Amount
Jun 16, 2026
Sell
Common Stock
S-Sale
Ambrose Allison
General Counsel
Officer 477
Value: $3K
Jun 16, 2026
Sell
Common Stock
S-Sale
Deykin Aaron
Chief Medical Officer
Officer 895
Value: $5K
Jun 16, 2026
Sell
Common Stock
S-Sale
Houghton Adam
Chief Business Officer
Officer 700
Value: $4K
Jun 16, 2026
Sell
Common Stock
S-Sale
Sutherland Everett Rand
Chief Executive Officer
CEO / President 2 095
Value: $12.8K
Jun 16, 2026
Sell
Common Stock
S-Sale
Gray Michael
CFO And COO
C-Suite Officer 853
Value: $5K
Jun 09, 2026
Buy
Stock Option (Right to Buy)
A-Award
Chimovits Erez
Director
Director 17 096
Value: $114.4K
Jun 09, 2026
Buy
Stock Option (Right to Buy)
A-Award
Ratcliffe Liam
Director
Director 17 096
Value: $114.4K
Jun 09, 2026
Buy
Stock Option (Right to Buy)
A-Award
Beckman Daniella
Director
Director 17 096
Value: $114.4K
Jun 09, 2026
Buy
Stock Option (Right to Buy)
A-Award
Fleming Harold Edward
Director
Director 17 096
Value: $114.4K
Jun 09, 2026
Buy
Stock Option (Right to Buy)
A-Award
Renaud Ronald C Jr
Director
Director 17 096
Value: $114.4K
Jun 09, 2026
Buy
Stock Option (Right to Buy)
A-Award
Ruddy Marcella K.
Director
Director 17 096
Value: $114.4K
Mar 16, 2026
Sell
Common Stock
S-Sale
Houghton Adam
Chief Business Officer
Officer 699
Value: $6K
Mar 16, 2026
Sell
Common Stock
S-Sale
Ambrose Allison
General Counsel
Officer 475
Value: $4K
Mar 16, 2026
Sell
Common Stock
S-Sale
Sutherland Everett Rand
Chief Executive Officer
CEO / President 2 093
Value: $19.4K
Mar 16, 2026
Sell
Common Stock
S-Sale
Deykin Aaron
Chief Medical Officer
Officer 894
Value: $8K
Mar 16, 2026
Sell
Common Stock
S-Sale
Gray Michael
CFO And COO
C-Suite Officer 852
Value: $8K
Jan 02, 2026
Buy
Stock Option (Right to Buy)
A-Award
Ambrose Allison
General Counsel
Officer 51 000
Value: $1.38M
Jan 02, 2026
Buy
Common Stock
A-Award
Ambrose Allison
General Counsel
Officer 17 000
Value: $460.2K
Jan 02, 2026
Buy
Stock Option (Right to Buy)
A-Award
Houghton Adam
Chief Business Officer
Officer 75 000
Value: $2.03M
Jan 02, 2026
Buy
Common Stock
A-Award
Houghton Adam
Chief Business Officer
Officer 25 000
Value: $676.8K
Jan 02, 2026
Buy
Stock Option (Right to Buy)
A-Award
Sutherland Everett Rand
Chief Executive Officer
CEO / President 225 000
Value: $6.09M
Jan 02, 2026
Buy
Common Stock
A-Award
Sutherland Everett Rand
Chief Executive Officer
CEO / President 75 000
Value: $2.03M
Jan 02, 2026
Buy
Common Stock
A-Award
Deykin Aaron
Chief Medical Officer
Officer 32 000
Value: $866.2K
Jan 02, 2026
Buy
Stock Option (Right to Buy)
A-Award
Deykin Aaron
Chief Medical Officer
Officer 96 000
Value: $2.60M
Jan 02, 2026
Buy
Common Stock
A-Award
Gray Michael
CFO And COO
C-Suite Officer 30 500
Value: $825.6K

About Insider Power

Insider Power is a proprietary algorithm developed by StockInvest.us to evaluate the significance of insider transactions. The calculation considers the size, type, and timing of transactions, as well as the insider’s role within the company.

It is important to note that, in general, there is little to no correlation between insider transactions and short-term stock price movements. In one of our studies, only 0.22%* of stocks with insider activity showed a measurable correlation — and even then, it was unclear whether the effect was caused by insider actions or simply by the stock’s broader trend.

While our algorithms are designed to highlight potentially meaningful signals, these cannot be regarded as statistically significant on their own. Insider trading activity should therefore be seen as informative rather than as direct trading guidance. The Insider Power metric was created to present this information in a clearer and more accessible way, helping investors better understand the possible context of insider activity.

* October 6th, 2025 - Tested on 5562 stocks

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