Prime Medicine Stock Forecast

Sell candidate since Oct 27, 2025 Loss -26.08%

The Prime Medicine, Inc. stock price gained 12.97% on the last trading day (Monday, 17th Nov 2025), rising from $3.37 to $3.81. During the last trading day the stock fluctuated 14.41% from a day low at $3.33 to a day high of $3.81. The price has fallen in 6 of the last 10 days and is down by -16.51% for this period. Volume has increased on the last day along with the price, which is a positive technical sign, and, in total, 4 million more shares were traded than the day before. In total, 8 million shares were bought and sold for approximately $31.78 million.

The stock lies in the lower part of a very wide and strong rising trend in the short term, and this may normally pose a very good buying opportunity. If the lower trend floor at $3.36 is broken, it will firstly indicate a slower rate of rising, but may also be an early warning for a trend shift. Given the current short-term trend, the stock is expected to rise 17.84% during the next 3 months and, with a 90% probability hold a price between $3.96 and $8.50 at the end of this 3-month period.

PRME Signals & Forecast

There are mixed signals in the stock today. The Prime Medicine, Inc. stock holds a buy signal from the short-term Moving Average; at the same time, however, the long-term average holds a general sell signal. Since the longterm average is above the short-term average there is a general sell signal in the stock giving a more negative forecast for the stock. On further gains, the stock will meet resistance from the long-term Moving Average at $5.08. On a fall, the stock will find some support from the short-term average at $3.62. A break-up through the long-term average will give another buy signal, while a fall below the short-term average will add another sell signal and strengthen the general signal. A sell signal was issued from a pivot top point on Thursday, October 02, 2025, and so far it has fallen -42.92%. Further fall is indicated until a new bottom pivot has been found. Furthermore, there is currently a sell signal from the 3 month Moving Average Convergence Divergence (MACD). Volume is rising along with the price. This is considered to be a good technical signal.

Support, Risk & Stop-loss for Prime Medicine, Inc. stock

On the downside, the stock finds support just below today's level from accumulated volume at $3.55 and $3.53. There is a natural risk involved when a stock is testing a support level, since if this is broken, the stock then may fall to the next support level. In this case, Prime Medicine, Inc. finds support just below today's level at $3.55. If this is broken, then the next support from accumulated volume will be at $3.53 and $3.24.

This stock may move very much during the day (volatility) and with a very large prediction interval from the Bollinger Band this stock is considered to be "very high risk". During the last day, the stock moved $0.480 between high and low, or 14.41%. For the last week, the stock has had daily average volatility of 12.37%.

Our recommended stop-loss: We hold a negative evaluation for this stock. No stop-loss is set.

Trading Expectations (PRME) For The Upcoming Trading Day Of Tuesday 18th

For the upcoming trading day on Tuesday, 18th we expect Prime Medicine, Inc. to open at $3.65, and during the day (based on 14 day Average True Range), to move between $3.57 and $4.04, which gives a possible trading interval of +/-$0.471 (+/-13.18%) up or down from last closing price. If Prime Medicine, Inc. takes out the full calculated possible swing range there will be an estimated 13.18% move between the lowest and the highest trading price during the day.

Since the stock is closer to the resistance from accumulated volume at $3.81 (0.08%) than the support at $3.55 (6.75%), our systems don't find the trading risk/reward intra-day attractive and any bets should be held until the stock is closer to the support level.

Is Prime Medicine, Inc. stock A Buy?

Prime Medicine, Inc. holds several negative signals and we believe that it will still perform weakly in the next couple of days or weeks. We, therefore, hold a negative evaluation of this stock.

Current score: -1.810 Sell Candidate Unchanged

Predicted Fair Opening Price

Predicted fair opening price on November 18, 2025 - $3.65 ( 4.15%).

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