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High volatility in Zymeworks Inc stock price on Monday which ended trading at $23.90
(Updated on Nov 17, 2025)

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Buy or Hold candidate since Nov 10, 2025 Gain 32.41%

The Zymeworks Inc stock price gained 29.05% on the last trading day (Monday, 17th Nov 2025), rising from $18.52 to $23.90. During the last trading day the stock fluctuated 16.12% from a day low at $22.55 to a day high of $26.19. The price has fallen in 6 of the last 10 days but is still up by 26.52% over the past 2 weeks. Volume has increased on the last day along with the price, which is a positive technical sign, and, in total, 10 million more shares were traded than the day before. In total, 11 million shares were bought and sold for approximately $266.03 million.

The stock has broken the wide and strong rising the short-term trend up and an even stronger rate of rising is indicated. For any reaction back there will now be support on the roof on the current trend broken at $20.51, a level that may pose a second chance to hit a runner. According to fan-theory $24.04 will be the next possible trend-top level and thereby pose a resistance level that may not be broken at the first attempt.

ZYME Signals & Forecast

The Zymeworks Inc stock holds buy signals from both short and long-term Moving Averages giving a positive forecast for the stock. Also, there is a general buy signal from the relation between the two signals where the short-term average is above the long-term average. On corrections down, there will be some support from the lines at $19.21 and $18.19. A breakdown below any of these levels will issue sell signals. A buy signal was issued from a pivot bottom point on Friday, November 07, 2025, and so far it has risen 45.20%. Further rise is indicated until a new top pivot has been found. Volume is rising along with the price. This is considered to be a good technical signal. Some negative signals were issued as well, and these may have some influence on the near short-term development. Furthermore, there is currently a sell signal from the 3 month Moving Average Convergence Divergence (MACD).

Support, Risk & Stop-loss for Zymeworks Inc stock

On the downside, the stock finds support just below today's level from accumulated volume at $19.30 and $18.47. There is a natural risk involved when a stock is testing a support level, since if this is broken, the stock then may fall to the next support level. In this case, Zymeworks Inc finds support just below today's level at $19.30. If this is broken, then the next support from accumulated volume will be at $18.47 and $18.05.

This stock has average movements during the day and with good trading volume, the risk is considered to be medium. During the last day, the stock moved $3.64 between high and low, or 16.12%. For the last week, the stock has had daily average volatility of 7.74%.

Our recommended stop-loss: $23.03 (-3.64%) (This stock has medium daily movements and this gives medium risk. There is a buy signal from a pivot bottom found 6 days ago.)

Trading Expectations (ZYME) For The Upcoming Trading Day Of Tuesday 18th

For the upcoming trading day on Tuesday, 18th we expect Zymeworks Inc to open at $24.21, and during the day (based on 14 day Average True Range), to move between $23.19 and $24.61, which gives a possible trading interval of +/-$1.42 (+/-6.10%) up or down from last closing price. If Zymeworks Inc takes out the full calculated possible swing range there will be an estimated 6.10% move between the lowest and the highest trading price during the day.

With no resistance above and support from accumulated volume @ $19.30, some $4.60 (19.25%) from the current price of $23.90, our system finds the risk reward attractive.

Is Zymeworks Inc stock A Buy?

Zymeworks Inc holds several positive signals, but we still don't find these to be enough for a buy candidate. At the current level, it should be considered as a hold candidate (hold or accumulate) in this position whilst awaiting further development. Due to some small weaknesses in the technical picture we have downgraded our analysis conclusion for this stock since the last evaluation from a Buy to a Hold candidate.

Current score: 0.000 Hold/Accumulate Downgraded

Zero in score indicates that our system is expecting high volatility and risk for the following trading day. Given the latest developments, we cannot determine the next direction as it may go both ways.

Predicted Fair Opening Price

Predicted fair opening price on November 18, 2025 - $24.21 ( 1.32%).

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ZYME Performance

Trading levels for ZYME

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Fibonacci Support & Resistance Levels

Level Price
R3 27.85 16.53%
R2 26.46 10.72%
R1 25.60 7.13%
Price 23.90
S1 22.83 -4.50%
S2 21.97 -8.09%
S3 20.58 -13.90%

Accumulated Volume Support & Resistance Levels

Level Price
R3 0 -
R2 0 -
R1 0 -
Price 23.90
S1 19.30 -19.25%
S2 18.47 -22.72%
S3 18.05 -24.48%

FAQ

What is the symbol for Zymeworks Inc Stock and on which exchange is it traded?
The symbol for Zymeworks Inc is ZYME and it is traded on the NYSE (New York Stock Exchange).

Should I buy or sell Zymeworks Inc Stock?
Zymeworks Inc holds several positive signals, but we still don't find these to be enough for a buy candidate. At the current level, it should be considered as a hold candidate (hold or accumulate) in this position whilst awaiting further development. Due to some small weaknesses in the technical picture we have downgraded our analysis conclusion for this stock since the last evaluation from a Buy to a Hold candidate.

How to buy Zymeworks Inc Stock?
Zymeworks Inc Stock can be purchased through just about any brokerage firm, including online brokerage services.
Click here for our free guide on how to buy Zymeworks Inc Stock.

What's the current price of Zymeworks Inc Stock?
As of the end of day on the Nov 17, 2025, the price of an Zymeworks Inc (ZYME) share was $23.90.

What is the 52-week high and low for Zymeworks Inc Stock?
The 52-week high for Zymeworks Inc Stock is $26.19 and the 52-week low is $9.03.

What is the market capitalization of Zymeworks Inc Stock?
As of the Nov 17, 2025, the market capitalization of Zymeworks Inc is 1.798B.

When is the next earnings date for Zymeworks Inc?
The upcoming earnings date for Zymeworks Inc is Mar 04, 2026.
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ABOUT ZYMEWORKS INC
Zymeworks
Zymeworks Inc., a clinical-stage biopharmaceutical company, discovers, develops, and commercializes biotherapeutics for the treatment of cancer. The company's lead product candidates include zanidatamab, a novel bispecific antibody that is in Phase 1 and Phase 2 clinical trials for the treatment of biliary tract, gastroesophageal adenocarcinomas, breast, and colorectal cancer; and ZW49, a biparatopic anti-human epidermal growth factor receptor 2 ...
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