NASDAQ:LYRA

Lyra Therapeutics Stock Insider Trading

Healthcare > Biotechnology

Buy LYRA

*Your capital is at risk

$0.495

+0 (+0%)

At Close: Jun 03, 2026

Lyra Therapeutics Stock Insider Power

Based on the 100 latest insides trades, we have calculated the insider power to be positive at 1.85. In total, the insiders bought 17.8M and sold 126.54K LYRA shares in the last 100 trades. The insider score can be negative despite buy/sell ratio being positive. The score focuses on the quality of the trades.

Insider Power (Last 100 transactions)	1.85
● Buy	17.8M shares
● Sell	126.54K shares
79% Buy Activity Negligible or No Correlation
Sell Signal Low Confidence Jun 01, 2026 Analysis Breakdown: Weakened by a contradictory positive Insider Power Score. Confidence increased due to high data reliability score of 100.

Historical Insider Trades

Date	Type	Person	Role	Amount
May 14, 2026 Sell	Common Stock D-Return	Smith W Bradford Director	Director	640 Value: $0
Apr 01, 2026 Sell	Common Stock D-Return	Palasis Maria Principal Executive Officer	Officer	2 000 Value: $0
Apr 01, 2026 Sell	Common Stock D-Return	Cavalier Jason Principal Financial Officer	Officer	667 Value: $0
Jan 06, 2026 Sell	Common Stock S-Sale	Palasis Maria President & CEO	CEO / President	1 702 Value: $6K
Jan 06, 2026 Sell	Common Stock S-Sale	Cavalier Jason Chief Financial Officer	C-Suite Officer	769 Value: $3K
Nov 13, 2025 Sell	Common Stock S-Sale	Perceptive Advisors Llc 10 Percent Owner	10% Owner	3 213 Value: $12.5K
Nov 13, 2025 Sell	Common Stock S-Sale	Perceptive Advisors Llc 10 Percent Owner	10% Owner	28 597 Value: $111.5K
Nov 12, 2025 Sell	Common Stock S-Sale	Perceptive Advisors Llc 10 Percent Owner	10% Owner	883 Value: $4K
Nov 12, 2025 Sell	Common Stock S-Sale	Perceptive Advisors Llc 10 Percent Owner	10% Owner	7 862 Value: $31.9K
Nov 11, 2025 Sell	Common Stock S-Sale	Perceptive Advisors Llc 10 Percent Owner	10% Owner	537 Value: $2K
Nov 11, 2025 Sell	Common Stock S-Sale	Perceptive Advisors Llc 10 Percent Owner	10% Owner	4 783 Value: $20.6K
Nov 10, 2025 Sell	Common Stock S-Sale	Perceptive Advisors Llc 10 Percent Owner	10% Owner	1 869 Value: $8K
Nov 10, 2025 Sell	Common Stock S-Sale	Perceptive Advisors Llc 10 Percent Owner	10% Owner	16 633 Value: $75.5K
Nov 07, 2025 Sell	Common Stock S-Sale	Perceptive Advisors Llc 10 Percent Owner	10% Owner	1 993 Value: $9K
Nov 07, 2025 Sell	Common Stock S-Sale	Perceptive Advisors Llc 10 Percent Owner	10% Owner	17 746 Value: $84.2K
Nov 06, 2025 Sell	Common Stock S-Sale	Perceptive Advisors Llc 10 Percent Owner	10% Owner	3 247 Value: $16.8K
Nov 06, 2025 Sell	Common Stock S-Sale	Perceptive Advisors Llc 10 Percent Owner	10% Owner	28 902 Value: $149.7K
Oct 01, 2025 Buy	Common Stock J-Other	Palasis Maria Insider	Other	0 Value: $0
Oct 01, 2025 Buy	Common Stock J-Other	Palasis Maria Insider	Other	0 Value: $0
Oct 01, 2025 Buy	Employee Stock Option (right to buy) A-Award	Palasis Maria President & CEO	CEO / President	3 667 Value: $1.11M
Oct 01, 2025 Buy	Employee Stock Option (right to buy) A-Award	Palasis Maria President & CEO	CEO / President	3 667 Value: $1.11M
Jul 10, 2025 Sell	Common Stock S-Sale	Palasis Maria President & CEO	CEO / President	1 565 Value: $13.9K
Jul 10, 2025 Sell	Common Stock S-Sale	Cavalier Jason Chief Financial Officer	C-Suite Officer	684 Value: $6K
Jul 10, 2025 Sell	Common Stock S-Sale	Cavalier Jason Chief Financial Officer	C-Suite Officer	684 Value: $6K
Jul 10, 2025 Sell	Common Stock S-Sale	Palasis Maria President & CEO	CEO / President	1 565 Value: $13.9K

About Insider Power

Insider Power is a proprietary algorithm developed by StockInvest.us to evaluate the significance of insider transactions. The calculation considers the size, type, and timing of transactions, as well as the insider’s role within the company.

It is important to note that, in general, there is little to no correlation between insider transactions and short-term stock price movements. In one of our studies, only 0.22%^* of stocks with insider activity showed a measurable correlation — and even then, it was unclear whether the effect was caused by insider actions or simply by the stock’s broader trend.

While our algorithms are designed to highlight potentially meaningful signals, these cannot be regarded as statistically significant on their own. Insider trading activity should therefore be seen as informative rather than as direct trading guidance. The Insider Power metric was created to present this information in a clearer and more accessible way, helping investors better understand the possible context of insider activity.

* October 6th, 2025 - Tested on 5562 stocks

ABOUT LYRA THERAPEUTICS INC.

Lyra Therapeutics, Inc., a clinical-stage therapeutics company, focuses on the development and commercialization of novel integrated drug and delivery solutions for the localized treatment of patients with ear, nose, and throat diseases. It's XTreo technology platform is designed to deliver medicines directly to the affected tissue for sustained periods with a single administration. The company's product candidates include LYR-210, an anti-inflam...

Read Full Profile Here