NASDAQ:PTGX

Protagonist Therapeutics Stock Insider Trading

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$95.41
+2.18 (+2.34%)
At Close: Jun 03, 2026

Protagonist Therapeutics Stock Insider Power

Based on the 100 latest insides trades, we have calculated the insider power to be negative at -84.03. In total, the insiders bought 1.16M and sold 569.31K PTGX shares in the last 100 trades. The insider score can be negative despite buy/sell ratio being positive. The score focuses on the quality of the trades.

Insider Power

(Last 100 transactions)
-84.03
Buy 1.16M shares
Sell 569.31K shares
61% Buy Activity
Weak Positive Correlation
Sell Signal Medium Confidence
Jan 20, 2026

Analysis Breakdown:

  • Strongly supported by a very low Insider Power Score of -84.03.
  • Confidence increased due to high data reliability score of 100.

Historical Insider Trades

Date Type Person Role Amount
Jan 02, 2026
Buy
Stock Option (right to buy)
A-Award
Giraudo Bryan
Director
Director 3 762
Value: $328.0K
Jan 02, 2026
Buy
Common Stock
A-Award
Giraudo Bryan
Director
Director 2 695
Value: $235.0K
Jan 02, 2026
Buy
Common Stock
A-Award
Waddill William D.
Director
Director 2 695
Value: $235.0K
Jan 02, 2026
Buy
Common Stock
A-Award
Selick Harold E
Director
Director 2 695
Value: $235.0K
Jan 02, 2026
Buy
Stock Option (right to buy)
A-Award
Selick Harold E
Director
Director 3 762
Value: $328.0K
Jan 02, 2026
Buy
Stock Option (right to buy)
A-Award
Waddill William D.
Director
Director 3 762
Value: $328.0K
Jan 02, 2026
Buy
Stock Option (right to buy)
A-Award
Williams Lewis T
Director
Director 3 762
Value: $328.0K
Jan 02, 2026
Buy
Stock Option (right to buy)
A-Award
Patel Dinesh V Ph D
President And CEO
CEO / President 120 200
Value: $10.5M
Jan 02, 2026
Buy
Stock Option (right to buy)
A-Award
Ali Asif
Chief Financial Officer
C-Suite Officer 32 000
Value: $2.79M
Jan 02, 2026
Buy
Common Stock
A-Award
Molina Arturo Md
Chief Medical Officer
Officer 25 600
Value: $2.23M
Nov 21, 2025
Sell
Common Stock
G-Gift
Patel Dinesh V Ph D
President And CEO
CEO / President 440
Value: $0
Nov 17, 2025
Sell
Common Stock
S-Sale
Molina Arturo Md
Chief Medical Officer
Officer 2 712
Value: $229.9K
Oct 10, 2025
Buy
Stock Option (right to buy)
M-Exempt
Waddill William D.
Director
Director 12 000
Value: $83.8K
Oct 10, 2025
Sell
Common Stock
S-Sale
Waddill William D.
Director
Director 8 000
Value: $702.5K
Oct 10, 2025
Sell
Common Stock
S-Sale
Waddill William D.
Director
Director 4 000
Value: $277.0K
Oct 10, 2025
Buy
Common Stock
M-Exempt
Waddill William D.
Director
Director 12 000
Value: $83.8K
Oct 10, 2025
Buy
Stock Option (right to buy)
M-Exempt
Waddill William D.
Director
Director 12 000
Value: $83.8K
Oct 10, 2025
Sell
Common Stock
S-Sale
Waddill William D.
Director
Director 8 000
Value: $702.5K
Oct 10, 2025
Sell
Common Stock
S-Sale
Waddill William D.
Director
Director 4 000
Value: $277.0K
Oct 10, 2025
Buy
Common Stock
M-Exempt
Waddill William D.
Director
Director 12 000
Value: $83.8K
Sep 22, 2025
Sell
Common Stock
S-Sale
Waddill William D.
Director
Director 4 000
Value: $257.0K
Sep 22, 2025
Sell
Common Stock
S-Sale
Waddill William D.
Director
Director 4 000
Value: $257.0K
Sep 16, 2025
Sell
Common Stock
G-Gift
Patel Dinesh V Ph D
President And CEO
CEO / President 620
Value: $0
Sep 16, 2025
Sell
Common Stock
G-Gift
Patel Dinesh V Ph D
President And CEO
CEO / President 620
Value: $0
Aug 27, 2025
Sell
Common Stock
S-Sale
Waddill William D.
Director
Director 4 000
Value: $237.0K

About Insider Power

Insider Power is a proprietary algorithm developed by StockInvest.us to evaluate the significance of insider transactions. The calculation considers the size, type, and timing of transactions, as well as the insider’s role within the company.

It is important to note that, in general, there is little to no correlation between insider transactions and short-term stock price movements. In one of our studies, only 0.22%* of stocks with insider activity showed a measurable correlation — and even then, it was unclear whether the effect was caused by insider actions or simply by the stock’s broader trend.

While our algorithms are designed to highlight potentially meaningful signals, these cannot be regarded as statistically significant on their own. Insider trading activity should therefore be seen as informative rather than as direct trading guidance. The Insider Power metric was created to present this information in a clearer and more accessible way, helping investors better understand the possible context of insider activity.

* October 6th, 2025 - Tested on 5562 stocks

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ABOUT PROTAGONIST THERAPEUTICS INC
Protagonist Therapeutics
Protagonist Therapeutics, Inc., a biopharmaceutical company, discovers and develops peptide-based therapeutic drugs to address hematology and blood disorders, and inflammatory and immunomodulatory diseases. It is developing rusfertide (PTG-300), an injectable hepcidin mimetic that is in Phase II clinical trials for the treatment of patients with polycythemia vera and hereditary hemochromatosis, as well as for the treatment of other blood disorder...
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