NASDAQ:VYNE

Vyne Therapeutics Stock Insider Trading

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$0.656
-0.0200 (-2.96%)
At Close: Jun 03, 2026

Vyne Therapeutics Stock Insider Power

Based on the 100 latest insides trades, we have calculated the insider power to be positive at 85.47. In total, the insiders bought 3.32M and sold 332.69K VYNE shares in the last 100 trades. The insider score can be negative despite buy/sell ratio being positive. The score focuses on the quality of the trades.

Insider Power

(Last 100 transactions)
85.47
Buy 3.32M shares
Sell 332.69K shares
36% Buy Activity
Moderate Negative Correlation
Sell Signal Low Confidence
Mar 31, 2026

Analysis Breakdown:

  • Signal is highly questionable due to a strongly contradictory positive Insider Power Score of 85.47.
  • Partially supported by a negative historical correlation.
  • Confidence increased due to high data reliability score of 100.

Historical Insider Trades

Date Type Person Role Amount
May 29, 2026
Buy
Common Stock
A-Award
Domzalski David
President And CEO
CEO / President 30 791
Value: $10K
Mar 31, 2026
Sell
Common Stock
F-InKind
Domzalski David
President And CEO
CEO / President 14 232
Value: $9K
Mar 31, 2026
Sell
Common Stock
F-InKind
Harsch Mutya
Chief Legal Officer And GC
Officer 4 007
Value: $2K
Mar 31, 2026
Sell
Common Stock
F-InKind
Stuart Iain
Chief Scientific Officer
Officer 2 876
Value: $2K
Mar 31, 2026
Sell
Common Stock
F-InKind
Zeronda Tyler
Chief Financial Officer
C-Suite Officer 4 007
Value: $2K
Dec 31, 2025
Sell
Common Stock
F-InKind
Harsch Mutya
Chief Legal Officer And GC
Officer 3 579
Value: $2K
Dec 31, 2025
Sell
Common Stock
F-InKind
Stuart Iain
Chief Scientific Officer
Officer 2 448
Value: $1K
Dec 31, 2025
Sell
Common Stock
F-InKind
Zeronda Tyler
Chief Financial Officer
C-Suite Officer 7 858
Value: $5K
Dec 31, 2025
Sell
Common Stock
F-InKind
Domzalski David
President And CEO
CEO / President 12 684
Value: $7K
Dec 12, 2025
Buy
Stock Option (right to buy)
A-Award
Barbari Sharon
Director
Director 20 000
Value: $8K
Dec 12, 2025
Buy
Stock Option (right to buy)
A-Award
Basta Steven L
Director
Director 20 000
Value: $8K
Dec 12, 2025
Buy
Stock Option (right to buy)
A-Award
Lepore Patrick G
Director
Director 20 000
Value: $8K
Dec 12, 2025
Buy
Stock Option (right to buy)
A-Award
Little Elisabeth Sandoval
Director
Director 20 000
Value: $8K
Sep 30, 2025
Sell
Common Stock
F-InKind
Zeronda Tyler
Chief Financial Officer
C-Suite Officer 3 420
Value: $1K
Sep 30, 2025
Sell
Common Stock
F-InKind
Stuart Iain
Chief Scientific Officer
Officer 2 453
Value: $822
Sep 30, 2025
Sell
Common Stock
F-InKind
Harsch Mutya
Chief Legal Officer And GC
Officer 3 581
Value: $1K
Sep 30, 2025
Sell
Common Stock
F-InKind
Domzalski David
President And CEO
CEO / President 12 676
Value: $4K
Sep 30, 2025
Sell
Common Stock
F-InKind
Domzalski David
President And CEO
CEO / President 12 676
Value: $4K
Sep 30, 2025
Sell
Common Stock
F-InKind
Harsch Mutya
Chief Legal Officer And GC
Officer 3 581
Value: $1K
Sep 30, 2025
Sell
Common Stock
F-InKind
Stuart Iain
Chief Scientific Officer
Officer 2 453
Value: $822
Sep 30, 2025
Sell
Common Stock
F-InKind
Zeronda Tyler
Chief Financial Officer
C-Suite Officer 3 420
Value: $1K
Jun 30, 2025
Sell
Common Stock
F-InKind
Zeronda Tyler
Chief Financial Officer
C-Suite Officer 3 420
Value: $6K
Jun 30, 2025
Sell
Common Stock
F-InKind
Stuart Iain
Chief Scientific Officer
Officer 2 453
Value: $4K
Jun 30, 2025
Sell
Common Stock
F-InKind
Harsch Mutya
Chief Legal Officer And GC
Officer 3 581
Value: $6K
Jun 30, 2025
Sell
Common Stock
F-InKind
Domzalski David
President And CEO
CEO / President 12 676
Value: $20.9K

About Insider Power

Insider Power is a proprietary algorithm developed by StockInvest.us to evaluate the significance of insider transactions. The calculation considers the size, type, and timing of transactions, as well as the insider’s role within the company.

It is important to note that, in general, there is little to no correlation between insider transactions and short-term stock price movements. In one of our studies, only 0.22%* of stocks with insider activity showed a measurable correlation — and even then, it was unclear whether the effect was caused by insider actions or simply by the stock’s broader trend.

While our algorithms are designed to highlight potentially meaningful signals, these cannot be regarded as statistically significant on their own. Insider trading activity should therefore be seen as informative rather than as direct trading guidance. The Insider Power metric was created to present this information in a clearer and more accessible way, helping investors better understand the possible context of insider activity.

* October 6th, 2025 - Tested on 5562 stocks

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ABOUT VYNE THERAPEUTICS INC
Vyne Therapeutics
VYNE Therapeutics Inc., a pharmaceutical company, focuses on developing various therapeutics for the treatment of immuno-inflammatory conditions. The company develops FCD105, a topical combination foam that has completed Phase III clinical trials for the treatment of moderate-to-severe acne vulgaris; and FMX114, a combination of tofacitinib, which is in Phase IIa preclinical trial for the treatment of mild-to-moderate atopic dermatitis. It is als...
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