NASDAQ:XLO

Xilio Therapeutics Stock Insider Trading

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$8.94
+0.150 (+1.71%)
At Close: Jun 22, 2026

Xilio Therapeutics Stock Insider Power

Based on the 100 latest insides trades, we have calculated the insider power to be negative at -52.54. In total, the insiders bought 27.82M and sold 16.56M XLO shares in the last 100 trades. The insider score can be negative despite buy/sell ratio being positive. The score focuses on the quality of the trades.

Insider Power

(Last 100 transactions)
-52.54
Buy 27.82M shares
Sell 16.56M shares
74% Buy Activity
Negligible or No Correlation
Sell Signal Medium Confidence
Jun 22, 2026

Analysis Breakdown:

  • Strongly supported by a very low Insider Power Score of -52.54.
  • Confidence increased due to high data reliability score of 100.

Historical Insider Trades

Date Type Person Role Amount
Nov 26, 2025
Sell
Series B Warrants (right to buy)
X-InTheMoney
Gilead Sciences, Inc.
10 Percent Owner
10% Owner 13 335 000
Value: $10.00M
Nov 26, 2025
Buy
Prefunded Warrants (right to buy)
X-InTheMoney
Gilead Sciences, Inc.
10 Percent Owner
10% Owner 13 335 000
Value: $1K
Nov 21, 2025
Sell
Stock Option (right to buy)
D-Return
Russo Rene
President And CEO
CEO / President 700 000
Value: $1.95M
Nov 21, 2025
Sell
Stock Option (right to buy)
D-Return
Russo Rene
President And CEO
CEO / President 350 000
Value: $941.5K
Nov 21, 2025
Sell
Stock Option (right to buy)
D-Return
Russo Rene
President And CEO
CEO / President 150 000
Value: $1.90M
Nov 21, 2025
Sell
Stock Option (right to buy)
D-Return
Russo Rene
President And CEO
CEO / President 50 041
Value: $800.7K
Nov 21, 2025
Sell
Stock Option (right to buy)
D-Return
Russo Rene
President And CEO
CEO / President 135 134
Value: $1.58M
Nov 21, 2025
Sell
Stock Option (right to buy)
D-Return
Russo Rene
President And CEO
CEO / President 473 334
Value: $2.79M
Nov 21, 2025
Sell
Stock Option (right to buy)
D-Return
Russo Rene
President And CEO
CEO / President 239 703
Value: $1.32M
Nov 21, 2025
Sell
Stock Option (right to buy)
D-Return
Russo Rene
President And CEO
CEO / President 100 000
Value: $1.38M
Nov 21, 2025
Buy
Stock Option (right to buy)
A-Award
Russo Rene
President And CEO
CEO / President 50 041
Value: $75.1K
Nov 21, 2025
Buy
Stock Option (right to buy)
A-Award
Russo Rene
President And CEO
CEO / President 100 000
Value: $150.0K
Nov 21, 2025
Buy
Stock Option (right to buy)
A-Award
Russo Rene
President And CEO
CEO / President 135 134
Value: $202.7K
Nov 21, 2025
Buy
Stock Option (right to buy)
A-Award
Russo Rene
President And CEO
CEO / President 150 000
Value: $225.0K
Nov 21, 2025
Sell
Stock Option (right to buy)
D-Return
Luptakova Katarina
Chief Medical Officer
Officer 106 000
Value: $295.7K
Nov 21, 2025
Sell
Stock Option (right to buy)
D-Return
Luptakova Katarina
Chief Medical Officer
Officer 15 000
Value: $35.6K
Nov 21, 2025
Buy
Stock Option (right to buy)
A-Award
Luptakova Katarina
Chief Medical Officer
Officer 25 000
Value: $37.5K
Nov 21, 2025
Buy
Stock Option (right to buy)
A-Award
Luptakova Katarina
Chief Medical Officer
Officer 44 210
Value: $66.3K
Nov 21, 2025
Buy
Stock Option (right to buy)
A-Award
Luptakova Katarina
Chief Medical Officer
Officer 625 000
Value: $525.6K
Nov 21, 2025
Buy
Stock Option (right to buy)
A-Award
Frankenfield Christopher James
Chief Financial Officer
C-Suite Officer 20 000
Value: $30.0K
Nov 21, 2025
Buy
Stock Option (right to buy)
A-Award
Brennan Kevin M.
SVP, Finance And Accounting
Officer 20 000
Value: $20.0K
Nov 21, 2025
Buy
Stock Option (right to buy)
A-Award
Frankenfield Christopher James
Chief Financial Officer
C-Suite Officer 23 786
Value: $35.7K
Nov 21, 2025
Buy
Stock Option (right to buy)
A-Award
Brennan Kevin M.
SVP, Finance And Accounting
Officer 25 000
Value: $25.0K
Nov 21, 2025
Buy
Stock Option (right to buy)
A-Award
Frankenfield Christopher James
Chief Financial Officer
C-Suite Officer 37 296
Value: $55.9K
Nov 21, 2025
Buy
Stock Option (right to buy)
A-Award
Frankenfield Christopher James
Chief Financial Officer
C-Suite Officer 45 000
Value: $67.5K

About Insider Power

Insider Power is a proprietary algorithm developed by StockInvest.us to evaluate the significance of insider transactions. The calculation considers the size, type, and timing of transactions, as well as the insider’s role within the company.

It is important to note that, in general, there is little to no correlation between insider transactions and short-term stock price movements. In one of our studies, only 0.22%* of stocks with insider activity showed a measurable correlation — and even then, it was unclear whether the effect was caused by insider actions or simply by the stock’s broader trend.

While our algorithms are designed to highlight potentially meaningful signals, these cannot be regarded as statistically significant on their own. Insider trading activity should therefore be seen as informative rather than as direct trading guidance. The Insider Power metric was created to present this information in a clearer and more accessible way, helping investors better understand the possible context of insider activity.

* October 6th, 2025 - Tested on 5562 stocks

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