NASDAQ:XLO

Xilio Therapeutics Stock Insider Trading

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$0.724
+0.0172 (+2.43%)
At Close: Nov 17, 2025

Xilio Therapeutics Stock Insider Power

Based on the 100 latest insides trades, we have calculated the insider power to be positive at 99.93. In total, the insiders bought 127.12M and sold 17.51K XLO shares in the last 100 trades. The insider score can be negative despite buy/sell ratio being positive. The score focuses on the quality of the trades.

Insider Power

(Last 100 transactions)
99.93
Buy 127.12M shares
Sell 17.51K shares
96% Buy Activity
Weak Positive Correlation
Buy Signal High Confidence
Jun 05, 2025

Analysis Breakdown:

  • Strongly supported by a very high Insider Power Score of 99.93.
  • Confidence increased due to high data reliability score of 100.
  • Supported by overwhelming buy-side pressure (96% buys).

Historical Insider Trades

Date Type Person Role Amount
Jun 17, 2025
Buy
Common Stock
P-Purchase
Shannon James Samuel
Director
Director 25 000
Value: $17.2K
Jun 17, 2025
Buy
Common Stock
P-Purchase
Shannon James Samuel
Director
Director 25 000
Value: $17.2K
Jun 16, 2025
Buy
Common Stock
P-Purchase
Shannon James Samuel
Director
Director 45 000
Value: $30.9K
Jun 16, 2025
Buy
Common Stock
P-Purchase
Russo Rene
President And CEO
CEO / President 36 289
Value: $24.7K
Jun 16, 2025
Buy
Common Stock
P-Purchase
Russo Rene
President And CEO
CEO / President 36 289
Value: $24.7K
Jun 16, 2025
Buy
Common Stock
P-Purchase
Shannon James Samuel
Director
Director 45 000
Value: $30.9K
Jun 11, 2025
Buy
Stock Option (right to buy)
A-Award
Ross Robert W.
Director
Director 31 000
Value: $21.5K
Jun 11, 2025
Buy
Stock Option (right to buy)
A-Award
Brennan Aoife
Director
Director 31 000
Value: $21.5K
Jun 11, 2025
Buy
Stock Option (right to buy)
A-Award
Bonstein Sara
Director
Director 31 000
Value: $21.5K
Jun 11, 2025
Buy
Stock Option (right to buy)
A-Award
Curran Daniel J.
Director
Director 31 000
Value: $21.5K
Jun 11, 2025
Buy
Stock Option (right to buy)
A-Award
Clancy Paul J
Director
Director 31 000
Value: $21.5K
Jun 11, 2025
Buy
Stock Option (right to buy)
A-Award
Xu Yuan
Director
Director 31 000
Value: $21.5K
Jun 11, 2025
Buy
Stock Option (right to buy)
A-Award
Shannon James Samuel
Director
Director 31 000
Value: $21.5K
Jun 11, 2025
Buy
Stock Option (right to buy)
A-Award
Rossi Christina
Director
Director 31 000
Value: $21.5K
Jun 11, 2025
Buy
Stock Option (right to buy)
A-Award
Rossi Christina
Director
Director 31 000
Value: $21.5K
Jun 11, 2025
Buy
Stock Option (right to buy)
A-Award
Shannon James Samuel
Director
Director 31 000
Value: $21.5K
Jun 11, 2025
Buy
Stock Option (right to buy)
A-Award
Xu Yuan
Director
Director 31 000
Value: $21.5K
Jun 11, 2025
Buy
Stock Option (right to buy)
A-Award
Clancy Paul J
Director
Director 31 000
Value: $21.5K
Jun 11, 2025
Buy
Stock Option (right to buy)
A-Award
Curran Daniel J.
Director
Director 31 000
Value: $21.5K
Jun 11, 2025
Buy
Stock Option (right to buy)
A-Award
Bonstein Sara
Director
Director 31 000
Value: $21.5K
Jun 11, 2025
Buy
Stock Option (right to buy)
A-Award
Brennan Aoife
Director
Director 31 000
Value: $21.5K
Jun 11, 2025
Buy
Stock Option (right to buy)
A-Award
Ross Robert W.
Director
Director 31 000
Value: $21.5K
Jun 10, 2025
Buy
Stock Option (right to buy)
A-Award
Bello Akintunde Olatokumbo
Director
Director 62 000
Value: $43.4K
Jun 10, 2025
Buy
Common Stock
J-Other
Bello Akintunde Olatokumbo
Insider
Other 0
Value: $0
Jun 10, 2025
Buy
Stock Option (right to buy)
A-Award
Bello Akintunde Olatokumbo
Director
Director 62 000
Value: $43.4K

About Insider Power

Insider Power is a proprietary algorithm developed by Stockinvest.us to evaluate the significance of insider transactions. The calculation considers the size, type, and timing of transactions, as well as the insider’s role within the company.

It is important to note that, in general, there is little to no correlation between insider transactions and short-term stock price movements. In one of our studies, only 0.22%* of stocks with insider activity showed a measurable correlation — and even then, it was unclear whether the effect was caused by insider actions or simply by the stock’s broader trend.

While our algorithms are designed to highlight potentially meaningful signals, these cannot be regarded as statistically significant on their own. Insider trading activity should therefore be seen as informative rather than as direct trading guidance. The Insider Power metric was created to present this information in a clearer and more accessible way, helping investors better understand the possible context of insider activity.

* October 6th, 2025 - Tested on 5562 stocks

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ABOUT XILIO THERAPEUTICS, INC.
Xilio Therapeutics
Xilio Therapeutics, Inc., a clinical-stage biotechnology company, develops immunotherapies to improve the immune system of cancer patients. Its checkpoint inhibitor program includes XTX101, a clinical-stage, tumor-selective anti-CTLA-4 mAb that is in Phase 1/2 clinical trials in patients with solid tumors. The company also develops cytokine programs, which comprises XTX202, a modified form of IL-2; XTX301, an IL-12 product candidate; and XTX401, ...
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