Schrodinger Earnings Calls
| Release date | May 05, 2026 |
| EPS estimate | -$0.560 |
| EPS actual | -$0.81 |
| EPS Surprise | -44.64% |
| Revenue estimate | 47.573M |
| Revenue actual | 58.587M |
| Revenue Surprise | 23.15% |
| Release date | Feb 25, 2026 |
| EPS estimate | -$0.130 |
| EPS actual | $0.440 |
| EPS Surprise | 438.46% |
| Revenue estimate | 83.756M |
| Revenue actual | 87.2M |
| Revenue Surprise | 4.11% |
| Release date | Nov 05, 2025 |
| EPS estimate | -$0.750 |
| EPS actual | -$0.450 |
| EPS Surprise | 40.00% |
| Revenue estimate | 83.607M |
| Revenue actual | 54.324M |
| Revenue Surprise | -35.02% |
| Release date | Aug 06, 2025 |
| EPS estimate | -$0.83 |
| EPS actual | -$0.590 |
| EPS Surprise | 28.92% |
| Revenue estimate | 50.346M |
| Revenue actual | 54.759M |
| Revenue Surprise | 8.77% |
Last 4 Quarters for Schrodinger
Below you can see how SDGR performed 4 days prior and 4 days after releasing the earnings report. Also, you can see the pre-estimates and the actual earnings. This information can give you a slight idea of what you might expect for the next quarter's release.
| Release date | Aug 06, 2025 |
| Price on release | $19.34 |
| EPS estimate | -$0.83 |
| EPS actual | -$0.590 |
| EPS surprise | 28.92% |
| Date | Price |
|---|---|
| Jul 31, 2025 | $20.33 |
| Aug 01, 2025 | $19.53 |
| Aug 04, 2025 | $19.99 |
| Aug 05, 2025 | $19.64 |
| Aug 06, 2025 | $19.34 |
| Aug 07, 2025 | $19.36 |
| Aug 08, 2025 | $19.21 |
| Aug 11, 2025 | $18.63 |
| Aug 12, 2025 | $18.85 |
| 4 days before | -4.87% |
| 4 days after | -2.53% |
| On release day | 0.103% |
| Change in period | -7.28% |
| Release date | Nov 05, 2025 |
| Price on release | $19.77 |
| EPS estimate | -$0.750 |
| EPS actual | -$0.450 |
| EPS surprise | 40.00% |
| Date | Price |
|---|---|
| Oct 30, 2025 | $20.46 |
| Oct 31, 2025 | $21.04 |
| Nov 03, 2025 | $20.55 |
| Nov 04, 2025 | $19.99 |
| Nov 05, 2025 | $19.77 |
| Nov 06, 2025 | $18.65 |
| Nov 07, 2025 | $17.78 |
| Nov 10, 2025 | $18.29 |
| Nov 11, 2025 | $18.30 |
| 4 days before | -3.37% |
| 4 days after | -7.44% |
| On release day | -5.67% |
| Change in period | -10.56% |
| Release date | Feb 25, 2026 |
| Price on release | $11.80 |
| EPS estimate | -$0.130 |
| EPS actual | $0.440 |
| EPS surprise | 438.46% |
| Date | Price |
|---|---|
| Feb 19, 2026 | $11.89 |
| Feb 20, 2026 | $11.53 |
| Feb 23, 2026 | $11.22 |
| Feb 24, 2026 | $11.30 |
| Feb 25, 2026 | $11.80 |
| Feb 26, 2026 | $12.76 |
| Feb 27, 2026 | $12.06 |
| Mar 02, 2026 | $12.15 |
| Mar 03, 2026 | $12.50 |
| 4 days before | -0.757% |
| 4 days after | 5.93% |
| On release day | 8.14% |
| Change in period | 5.13% |
| Release date | May 05, 2026 |
| Price on release | $12.87 |
| EPS estimate | -$0.560 |
| EPS actual | -$0.81 |
| EPS surprise | -44.64% |
| Date | Price |
|---|---|
| Apr 29, 2026 | $11.76 |
| Apr 30, 2026 | $11.96 |
| May 01, 2026 | $12.39 |
| May 04, 2026 | $12.90 |
| May 05, 2026 | $12.87 |
| May 06, 2026 | $12.98 |
| May 07, 2026 | $13.28 |
| May 08, 2026 | $13.13 |
| May 11, 2026 | $12.72 |
| 4 days before | 9.44% |
| 4 days after | -1.17% |
| On release day | 0.85% |
| Change in period | 8.16% |
Schrodinger Earnings Call Transcript Summary of Q1 2026
Schrodinger reported a strong start to 2026 with ACV of $28.4M in Q1 (up 12% YoY) and trailing 4-quarter ACV of $201M. Total Q1 revenue was $58.6M, driven by software ($35.6M, with hosted revenue now 34% of software) and drug discovery ($22.9M). The company is accelerating its shift from on‑premise to hosted, throughput-based licensing (targeting ~75% hosted in three years), which smooths near-term recognized revenue but should create more predictable, scalable long‑term growth. Schrodinger highlighted growing customer demand, positive early adoption of its predictive toxicology solution, and the upcoming early‑access release of Bunsen — an agentic AI “co‑scientist” expected to boost throughput and broaden usage. The therapeutics business continues to validate the platform: Lilly’s announced $2.3B acquisition of Ajax (Schrodinger ~6% equity) and multiple prior exits demonstrate the commercial impact of Schrodinger‑co‑discovered molecules. Q1 operating expenses eased to $78M, net loss was $60M, and cash and marketable securities stood at $406M. Full‑year 2026 guidance was maintained: ACV $218–228M (10–15% growth) and drug discovery revenue $55–65M. The company expects to largely complete clinical activities by end of 2026, with R&D spend for clinical wind‑down of ~$10–15M for the year. Management emphasized continued investment in sales & marketing, disciplined expense management, and that any Ajax proceeds will be cash upside to the balance sheet.
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