NASDAQ:PRME

Prime Medicine Stock Insider Trading

Healthcare > Biotechnology

Buy PRME

*Your capital is at risk

$2.92

-0.100 (-3.31%)

At Close: Jul 31, 2026

Prime Medicine Stock Insider Power

Based on the 100 latest insides trades, we have calculated the insider power to be negative at -19.48. In total, the insiders bought 6.74M and sold 2.97M PRME shares in the last 100 trades. The insider score can be negative despite buy/sell ratio being positive. The score focuses on the quality of the trades.

Insider Power (Last 100 transactions)	-19.48
● Buy	6.74M shares
● Sell	2.97M shares
56% Buy Activity Weak Negative Correlation
Buy Signal Low Confidence Apr 16, 2026 Analysis Breakdown: Weakened by a contradictory negative Insider Power Score. Confidence increased due to high data reliability score of 100.

Historical Insider Trades

Date	Type	Person	Role	Amount
Aug 01, 2025 Sell	Stock Option (right to buy) D-Return	Reine Allan Chief Executive Officer	CEO / President	850 000 Value: $5.78M
Aug 01, 2025 Buy	Stock Option (right to buy) A-Award	Alenson Carman See Remarks	Officer	90 498 Value: $365.6K
Aug 01, 2025 Buy	Stock Option (right to buy) A-Award	Alenson Carman See Remarks	Officer	16 083 Value: $65.0K
Aug 01, 2025 Buy	Stock Option (right to buy) A-Award	Alenson Carman See Remarks	Officer	6 254 Value: $25.3K
Aug 01, 2025 Sell	Stock Option (right to buy) D-Return	Alenson Carman See Remarks	Officer	90 498 Value: $1.11M
Aug 01, 2025 Sell	Stock Option (right to buy) D-Return	Alenson Carman See Remarks	Officer	16 083 Value: $175.6K
Aug 01, 2025 Buy	Stock Option (right to buy) A-Award	Reine Allan Chief Executive Officer	CEO / President	850 000 Value: $3.43M
Aug 01, 2025 Sell	Stock Option (right to buy) D-Return	Cahill Thomas Director	Director	45 000 Value: $345.6K
Aug 01, 2025 Sell	Stock Option (right to buy) D-Return	Cahill Thomas Director	Director	39 062 Value: $579.3K
Aug 01, 2025 Buy	Stock Option (right to buy) A-Award	Cahill Thomas Director	Director	39 062 Value: $157.8K
Aug 01, 2025 Buy	Stock Option (right to buy) A-Award	Cahill Thomas Director	Director	45 000 Value: $181.8K
Aug 01, 2025 Sell	Stock Option (right to buy) D-Return	Chung Wendy Director	Director	13 510 Value: $142.4K
Aug 01, 2025 Sell	Stock Option (right to buy) D-Return	Chung Wendy Director	Director	45 000 Value: $345.6K
Aug 01, 2025 Sell	Stock Option (right to buy) D-Return	Chung Wendy Director	Director	9 006 Value: $153.1K
Aug 01, 2025 Sell	Stock Option (right to buy) D-Return	Chung Wendy Director	Director	39 062 Value: $579.3K
Aug 01, 2025 Buy	Stock Option (right to buy) A-Award	Chung Wendy Director	Director	9 006 Value: $36.4K
Aug 01, 2025 Buy	Stock Option (right to buy) A-Award	Chung Wendy Director	Director	13 510 Value: $54.6K
Aug 01, 2025 Buy	Stock Option (right to buy) A-Award	Chung Wendy Director	Director	39 062 Value: $157.8K
Aug 01, 2025 Buy	Stock Option (right to buy) A-Award	Chung Wendy Director	Director	45 000 Value: $181.8K
Aug 01, 2025 Sell	Stock Option (right to buy) D-Return	Foster-cheek Kaye I Director	Director	45 000 Value: $345.6K
Aug 01, 2025 Sell	Stock Option (right to buy) D-Return	Foster-cheek Kaye I Director	Director	13 510 Value: $147.5K
Aug 01, 2025 Sell	Stock Option (right to buy) D-Return	Foster-cheek Kaye I Director	Director	9 006 Value: $153.1K
Aug 01, 2025 Sell	Stock Option (right to buy) D-Return	Foster-cheek Kaye I Director	Director	39 062 Value: $579.3K
Aug 01, 2025 Buy	Stock Option (right to buy) A-Award	Foster-cheek Kaye I Director	Director	9 006 Value: $36.4K
Aug 01, 2025 Buy	Stock Option (right to buy) A-Award	Foster-cheek Kaye I Director	Director	13 510 Value: $54.6K

About Insider Power

Insider Power is a proprietary algorithm developed by StockInvest.us to evaluate the significance of insider transactions. The calculation considers the size, type, and timing of transactions, as well as the insider’s role within the company.

It is important to note that, in general, there is little to no correlation between insider transactions and short-term stock price movements. In one of our studies, only 0.22%^* of stocks with insider activity showed a measurable correlation — and even then, it was unclear whether the effect was caused by insider actions or simply by the stock’s broader trend.

While our algorithms are designed to highlight potentially meaningful signals, these cannot be regarded as statistically significant on their own. Insider trading activity should therefore be seen as informative rather than as direct trading guidance. The Insider Power metric was created to present this information in a clearer and more accessible way, helping investors better understand the possible context of insider activity.

* October 6th, 2025 - Tested on 5562 stocks