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Ionis Pharmaceuticals stock downgraded to Buy Candidate
(Updated on Jun 11, 2025)

Buy or Hold candidate since May 29, 2025 Gain 8.16%

The Ionis Pharmaceuticals stock price fell by -1.76% on the last day (Wednesday, 11th Jun 2025) from $36.84 to $36.19. During the last trading day the stock fluctuated 2.31% from a day low at $36.10 to a day high of $36.94. The price has risen in 9 of the last 10 days and is up by 11.59% over the past 2 weeks. Volume fell on the last day along with the stock, which is actually a good sign as volume should follow the stock. On the last day, the trading volume fell by -32 thousand shares and in total, 2 million shares were bought and sold for approximately $56.21 million.

The stock lies in the upper part of a very wide and strong rising trend in the short term, and this may normally pose a very good selling opportunity for the short-term trader as reaction back towards the lower part of the trend can be expected. A break-up at the top trend line at $36.91 will firstly indicate a stronger rate of rising. Given the current short-term trend, the stock is expected to rise 14.09% during the next 3 months and, with a 90% probability hold a price between $32.74 and $42.11 at the end of this 3-month period.

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IONS Signals & Forecast

The Ionis Pharmaceuticals stock holds buy signals from both short and long-term Moving Averages giving a positive forecast for the stock. Also, there is a general buy signal from the relation between the two signals where the short-term average is above the long-term average. On corrections down, there will be some support from the lines at $35.74 and $33.06. A breakdown below any of these levels will issue sell signals. Furthermore, there is a buy signal from the 3 month Moving Average Convergence Divergence (MACD). Some negative signals were issued as well, and these may have some influence on the near short-term development. A sell signal was issued from a pivot top point on Tuesday, June 10, 2025, and so far it has fallen -1.76%. Further fall is indicated until a new bottom pivot has been found. Volume fell together with the price during the last trading day and this reduces the overall risk as volume should follow the price movements.

Support, Risk & Stop-loss for Ionis Pharmaceuticals stock

On the downside, the stock finds support just below today's level from accumulated volume at $32.43 and $27.77. There is a natural risk involved when a stock is testing a support level, since if this is broken, the stock then may fall to the next support level. In this case, Ionis Pharmaceuticals finds support just below today's level at $32.43. If this is broken, then the next support from accumulated volume will be at $27.77 and $27.26.

This stock has average movements during the day and with good trading volume, the risk is considered to be medium. During the last day, the stock moved $0.84 between high and low, or 2.31%. For the last week, the stock has had daily average volatility of 2.82%.

Our recommended stop-loss: $34.64 (-4.27%) (This stock has medium daily movements and this gives medium risk. There is a sell signal from a pivot top found 1 day ago.)

Trading Expectations (IONS) For The Upcoming Trading Day Of Thursday 12th

For the upcoming trading day on Thursday, 12th we expect Ionis Pharmaceuticals to open at $36.41, and during the day (based on 14 day Average True Range), to move between $35.04 and $37.34, which gives a possible trading interval of +/-$1.15 (+/-3.18%) up or down from last closing price. If Ionis Pharmaceuticals takes out the full calculated possible swing range there will be an estimated 6.37% move between the lowest and the highest trading price during the day.

Since the stock is closer to the resistance from accumulated volume at $36.76 (1.58%) than the support at $32.43 (10.39%), our systems don't find the trading risk/reward intra-day attractive and any bets should be held until the stock is closer to the support level.

Is Ionis Pharmaceuticals stock A Buy?

Several short-term signals, along with a general good trend, are positive and we conclude that the current level may hold a buying opportunity as there is a fair chance for Ionis Pharmaceuticals stock to perform well in the short-term. Due to some small weaknesses in the technical picture we have downgraded our analysis conclusion for this stock since the last evaluation from a Strong Buy to a Buy candidate.

Current score: 1.644 Buy Candidate Downgraded

Predicted Fair Opening Price

Predicted fair opening price on June 12, 2025 - $36.41 ( 0.603%).

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IONS Performance

Trading levels for IONS

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Fibonacci Support & Resistance Levels

Level Price
R3 37.24 2.91%
R2 36.92 2.03%
R1 36.73 1.48%
Price 36.19
S1 36.09 -0.278%
S2 35.89 -0.82%
S3 35.57 -1.70%

Accumulated Volume Support & Resistance Levels

Level Price
R3 0 -
R2 36.84 1.80%
R1 36.76 1.58%
Price 36.19
S1 32.43 -10.39%
S2 27.77 -23.27%
S3 27.26 -24.68%

FAQ

What is the symbol for Ionis Pharmaceuticals Stock and on which exchange is it traded?
The symbol for Ionis Pharmaceuticals is IONS and it is traded on the NASDAQ (NASDAQ Stock Exchange).

Should I buy or sell Ionis Pharmaceuticals Stock?
Several short-term signals, along with a general good trend, are positive and we conclude that the current level may hold a buying opportunity as there is a fair chance for Ionis Pharmaceuticals stock to perform well in the short-term. Due to some small weaknesses in the technical picture we have downgraded our analysis conclusion for this stock since the last evaluation from a Strong Buy to a Buy candidate.

How to buy Ionis Pharmaceuticals Stock?
Ionis Pharmaceuticals Stock can be purchased through just about any brokerage firm, including online brokerage services.
Click here for our free guide on how to buy Ionis Pharmaceuticals Stock.

What's the current price of Ionis Pharmaceuticals Stock?
As of the end of day on the Jun 11, 2025, the price of an Ionis Pharmaceuticals (IONS) share was $36.19.

What is the 52-week high and low for Ionis Pharmaceuticals Stock?
The 52-week high for Ionis Pharmaceuticals Stock is $52.34 and the 52-week low is $23.95.

What is the market capitalization of Ionis Pharmaceuticals Stock?
As of the Jun 11, 2025, the market capitalization of Ionis Pharmaceuticals is 5.76B.

When is the next earnings date for Ionis Pharmaceuticals?
The upcoming earnings date for Ionis Pharmaceuticals is Jul 30, 2025.
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ABOUT IONIS PHARMACEUTICALS
Ionis Pharmaceuticals
Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapeutics in the United States. The company offers SPINRAZA for spinal muscular atrophy (SMA) in pediatric and adult patients; TEGSEDI, an injection for the treatment of polyneuropathy of hereditary transthyretin-mediated amyloidosis in adults; and WAYLIVRA, a treatment for familial chylomicronemia syndrome and familial partial lipodystrophy. It also develops medicines for various...
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