NASDAQ:IONS

Ionis Pharmaceuticals Stock Insider Trading

etoro logo Buy IONS
*Your capital is at risk
$81.80
+2.61 (+3.30%)
At Close: Jul 02, 2026

Ionis Pharmaceuticals Stock Insider Power

Based on the 100 latest insides trades, we have calculated the insider power to be negative at -78.21. In total, the insiders bought 1.04M and sold 578.42K IONS shares in the last 100 trades. The insider score can be negative despite buy/sell ratio being positive. The score focuses on the quality of the trades.

Insider Power

(Last 100 transactions)
-78.21
Buy 1.04M shares
Sell 578.42K shares
68% Buy Activity
Moderate Negative Correlation
Sell Signal High Confidence
Jan 16, 2026

Analysis Breakdown:

  • Strongly supported by a very low Insider Power Score of -78.21.
  • Partially supported by a negative historical correlation.
  • Confidence increased due to high data reliability score of 100.

Historical Insider Trades

Date Type Person Role Amount
Jun 26, 2026
Sell
Common Stock
S-Sale
Schneider Eugene
EVP, Chf Clinical Develop Ofcr
Officer 26 000
Value: $2.11M
Jun 26, 2026
Buy
Common Stock
M-Exempt
Schneider Eugene
EVP, Chf Clinical Develop Ofcr
Officer 26 000
Value: $1.58M
Jun 26, 2026
Sell
Common Stock
S-Sale
O'neil Patrick R.
EVP Clo & General Counsel
Officer 3 069
Value: $245.5K
Jun 26, 2026
Buy
Non-Qualified Stock Option (right to buy)
M-Exempt
Baroldi Joseph
EVP, Chief Business Officer
Officer 3 866
Value: $219.5K
Jun 26, 2026
Buy
Non-Qualified Stock Option (right to buy)
M-Exempt
Baroldi Joseph
EVP, Chief Business Officer
Officer 1 769
Value: $57.7K
Jun 26, 2026
Sell
Common Stock
S-Sale
Baroldi Joseph
EVP, Chief Business Officer
Officer 5 635
Value: $451.7K
Jun 26, 2026
Buy
Common Stock
M-Exempt
Baroldi Joseph
EVP, Chief Business Officer
Officer 3 866
Value: $219.5K
Jun 26, 2026
Buy
Common Stock
M-Exempt
Baroldi Joseph
EVP, Chief Business Officer
Officer 1 769
Value: $57.7K
Jun 26, 2026
Buy
Non-Qualified Stock Option (right to buy)
M-Exempt
Schneider Eugene
EVP, Chf Clinical Develop Ofcr
Officer 26 000
Value: $1.58M
Jun 26, 2026
Sell
Common Stock
S-Sale
Monia Brett P
Chief Executive Officer
CEO / President 50 000
Value: $4.03M
Jun 26, 2026
Buy
Non-Qualified Stock Option (right to buy)
M-Exempt
Monia Brett P
Chief Executive Officer
CEO / President 50 000
Value: $2.84M
Jun 26, 2026
Buy
Common Stock
M-Exempt
Monia Brett P
Chief Executive Officer
CEO / President 50 000
Value: $2.84M
Jun 25, 2026
Sell
Common Stock
S-Sale
Monia Brett P
Chief Executive Officer
CEO / President 21 072
Value: $1.65M
Jun 25, 2026
Buy
Non-Qualified Stock Option (right to buy)
M-Exempt
Monia Brett P
Chief Executive Officer
CEO / President 21 072
Value: $686.9K
Jun 25, 2026
Sell
Common Stock
S-Sale
Swayze Eric
EVP Research
Officer 10 602
Value: $839.5K
Jun 25, 2026
Buy
Common Stock
M-Exempt
Monia Brett P
Chief Executive Officer
CEO / President 21 072
Value: $686.9K
Jun 24, 2026
Sell
Common Stock
S-Sale
Monia Brett P
Chief Executive Officer
CEO / President 14 565
Value: $1.14M
Jun 24, 2026
Buy
Non-Qualified Stock Option (right to buy)
M-Exempt
Monia Brett P
Chief Executive Officer
CEO / President 14 565
Value: $474.8K
Jun 24, 2026
Buy
Common Stock
M-Exempt
Monia Brett P
Chief Executive Officer
CEO / President 14 565
Value: $474.8K
Jun 15, 2026
Buy
Non-Qualified Stock Option (right to buy)
M-Exempt
Berthelsen Spencer R
Director
Director 8 000
Value: $195.4K
Jun 15, 2026
Sell
Common Stock
S-Sale
Berthelsen Spencer R
Director
Director 8 000
Value: $587.9K
Jun 15, 2026
Buy
Common Stock
M-Exempt
Berthelsen Spencer R
Director
Director 8 000
Value: $195.4K
Jun 12, 2026
Buy
Common Stock
M-Exempt
Kordasiewicz Holly B.
EVP, Chief Development Officer
Officer 19 895
Value: $1.13M
Jun 12, 2026
Buy
Common Stock
M-Exempt
Kordasiewicz Holly B.
EVP, Chief Development Officer
Officer 12 000
Value: $391.2K
Jun 12, 2026
Buy
Common Stock
M-Exempt
Kordasiewicz Holly B.
EVP, Chief Development Officer
Officer 21 000
Value: $1.28M

About Insider Power

Insider Power is a proprietary algorithm developed by StockInvest.us to evaluate the significance of insider transactions. The calculation considers the size, type, and timing of transactions, as well as the insider’s role within the company.

It is important to note that, in general, there is little to no correlation between insider transactions and short-term stock price movements. In one of our studies, only 0.22%* of stocks with insider activity showed a measurable correlation — and even then, it was unclear whether the effect was caused by insider actions or simply by the stock’s broader trend.

While our algorithms are designed to highlight potentially meaningful signals, these cannot be regarded as statistically significant on their own. Insider trading activity should therefore be seen as informative rather than as direct trading guidance. The Insider Power metric was created to present this information in a clearer and more accessible way, helping investors better understand the possible context of insider activity.

* October 6th, 2025 - Tested on 5562 stocks

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ABOUT IONIS PHARMACEUTICALS
Ionis Pharmaceuticals
Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapeutics in the United States. The company offers SPINRAZA for spinal muscular atrophy (SMA) in pediatric and adult patients; TEGSEDI, an injection for the treatment of polyneuropathy of hereditary transthyretin-mediated amyloidosis in adults; and WAYLIVRA, a treatment for familial chylomicronemia syndrome and familial partial lipodystrophy. It also develops medicines for various...
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